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Merck
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Key Documents

49909

Sigma-Aldrich

Lanolin

tested according to Ph. Eur.

Sinónimos:

Adeps lanae, Wool fat

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About This Item

Número de CAS:
EC Number:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

agency

USP/NF
tested according to Ph. Eur.

Quality Level

autoignition temp.

833 °F

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General description

Lanolin is a wool fat. It is a semisolid of high viscosity. Contact allergy to lanolin (wool alcohols), an important sensitizer, in a central London teaching hospital patch-test population has been reported. Simplified extraction of organochlorine and organophosphorus pesticides, frequently found in lanolin, has been proposed. It is utilized as an emulsifier in pharmaceutical and cosmetic formulations.

Application

Lanolin was used to compose the lanolin ointment to estimate the release kinetics of izotretinon and heparin from various semisolid dosage forms by UV-VIS spectroscopy. It was used to prepare the emulsified aqueous solutions containing crystalline dicarboxylic acid. It may be added as excipient to compose a nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect.
Zobrist B, et al.
Atmospheric Chemistry and Physics, 6(10), 3115-3129 (2006)
H Diserens
Journal - Association of Official Analytical Chemists, 72(6), 991-993 (1989-11-01)
In the proposed method, a light petroleum solution of lanolin (wool fat) is adsorbed on diatomaceous earth in an Extrelut column, and the pesticides are eluted with acetonitrile saturated with light petroleum. After evaporation to a small volume, the extract
Flora B de Waard-van der Spek et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 26(7), 598-606 (2015-08-20)
Allergic contact dermatitis (ACD) in children appears to be on the increase, and contact sensitization may already begin in infancy. The diagnosis of contact dermatitis requires a careful evaluation of a patient's clinical history, physical examination, and skin testing. Patch
Wenjian Zhang et al.
Nanotechnology, 25(12), 125101-125101 (2014-02-28)
A novel nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye has been successfully developed. The excipients used as semisolid lipids were petrolatum and lanolin, as used in conventional eye ointment, which were coupled with medium-chain triglycerides
M Abou-Dakn et al.
Skin pharmacology and physiology, 24(1), 27-35 (2010-08-20)
Painful and/or damaged nipples associated with breastfeeding are common and represent a challenge for both the persons experiencing nipple pain and/or trauma and for those providing treatment. However, evidence-based data has been insufficient to demonstrably minimize these common reasons for

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