341088

1,9-Dimethyl-Methylene Blue zinc chloride double salt

Dye content 80 %

• Sinónimos: DMMB, Taylor’s Blue
• Fórmula empírica (notación de Hill): C₁₈H₂₂ClN₃S · 0.5ZnCl₂
• Número de CAS: 931418-92-7
• Peso molecular: 416.05
• MDL number: MFCD19686959
• UNSPSC Code: 12171500
• PubChem Substance ID: 24860900
• NACRES: NA.47

Propiedades

• form: powder
• Quality Level: 200
• composition: Dye content, 80%
• impurities: <20% water
• mp: 250 °C (dec.) (lit.)
• λmax: 649 nm
• ε (extinction coefficient): ≥10000 at 243-249 nm in H₂O; ≥18000 at 285-291 nm in H₂O; ≥25000 at 594-600 nm in H₂O; ≥35000 at 646-652 nm in H₂O
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Cl-].[Cl-].Cl[Zn]Cl.CN(C)c1cc(C)c2N=C3C(C)=C\C(C=C3Sc2c1)=[N+](/C)C.CN(C)c4cc(C)c5N=C6C(C)=C\C(C=C6Sc5c4)=[N+](/C)C
• InChI: 1S/2C18H22N3S.4ClH.Zn/c2*1-11-7-13(20(3)4)9-15-17(11)19-18-12(2)8-14(21(5)6)10-16(18)22-15;;;;;/h2*7-10H,1-6H3;4*1H;/q2*+1;;;;;+2/p-4
• InChI key: MKLBAKXCEQNMBC-UHFFFAOYSA-J

Descripción

Application

1,9-Dimethyl-Methylene Blue zinc chloride double salt has been used for the quantification of sulfated glycosaminoglycans.

DMMB is a cationic dye that specifically binds to sulfated glycosaminoglycans (sGAG) with an absorbance at ~525 nm. It has been used to quantitate glycosaminoglyans such as chondroitin sulfate, keratin sulfate, and heparan sulfate and sGAG chains in proteoglycans. One limitation to this method The sGAG-DMMB complex is unstable in solution and may precipitate. Precipitation of the complex was shown to improve stability.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves