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Merck

02671

Supelco

Carbon tetrachloride

analytical standard

Sinónimos:

Tetrachloromethane

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About This Item

Fórmula empírica (notación de Hill):
CCl4
Número de CAS:
Peso molecular:
153.82
Beilstein/REAXYS Number:
1098295
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

5.32 (vs air)

vapor pressure

143 mmHg ( 30 °C)
91 mmHg ( 20 °C)

assay

≥99.95% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.460 (lit.)
n20/D 1.460

bp

76-77 °C (lit.)

mp

−23 °C (lit.)

density

1.594 g/mL at 25 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

ClC(Cl)(Cl)Cl

InChI

1S/CCl4/c2-1(3,4)5

InChI key

VZGDMQKNWNREIO-UHFFFAOYSA-N

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General description

Carbon tetrachloride (CCl4) is a clear, colourless, volatile and very stable chlorinated hydrocarbon. It is widely used as a solvent for fats, varnishes, oils, lacquers, resins, and rubber waxes. It is also used as a dry-cleaning agent, as a refrigerant, and as a starting material in the manufacturing of organic compounds.

Application

CCl4 may have been used as reference standard in colorimetric analysis to determine CCl4 in fatty liver sample.

Other Notes

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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation

target_organs

Liver,Kidney

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Biochemical changes in carbon tetrachloride fatty liver: concentration of carbon tetrachloride in liver and blood.
RECKNAGEL RO, LITTERIA M.
The American Journal of Pathology, 36, 521-531 (1960)
Bruce D. Craig, David S. Anderson
Handbook of Corrosion Data, 257-257 (1994)
Lutz W D Weber et al.
Critical reviews in toxicology, 33(2), 105-136 (2003-04-24)
The use of many halogenated alkanes such as carbon tetrachloride (CCl4), chloroform (CHCl3) or iodoform (CHI3), has been banned or severely restricted because of their distinct toxicity. Yet CCl4 continues to provide an important service today as a model substance
Samuele De Minicis et al.
Hepatology (Baltimore, Md.), 59(5), 1738-1749 (2013-08-21)
Nonalcoholic fatty liver disease (NAFLD) may lead to hepatic fibrosis. Dietary habits affect gut microbiota composition, whereas endotoxins produced by Gram-negative bacteria stimulate hepatic fibrogenesis. However, the mechanisms of action and the potential effect of microbiota in the liver are
Samar Basu
Toxicology, 189(1-2), 113-127 (2003-06-25)
Hepatic injury through carbon tetrachloride (CCl(4)) induced lipid peroxidation is well known and has been extensively used in the experimental models to understand the cellular mechanisms behind oxidative damage and further to evaluate the therapeutic potential of drugs and dietary

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