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RKTX2MAG-37K

Millipore

MILLIPLEX® Rat Kidney Toxicity Magnetic Bead Panel 2 - Toxicity Multiplex Assay

The analytes available for this multiplex kit are: Albumin, AGP, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL.

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About This Item

Código UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Nivel de calidad

200

reactividad de especies

rat

fabricante / nombre comercial

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.00-2 ng/mL
(EGF)
standard curve range: 0.01-10 ng/mL
(Lipocalin-2/NGAL)
standard curve range: 0.01-8 ng/mL
(Cystatin C)
standard curve range: 0.48-350 ng/mL
(β2M)
standard curve range: 1.37-1,000 ng/mL
(AGP)
standard curve range: 10.97-8,000 ng/mL
(Albumin)
inter-assay cv: <15%
intra-assay cv: <10%
(All other analytes)
inter-assay cv: <20%
intra-assay cv: <15%
(AGP)

técnicas

multiplexing: suitable

método de detección

fluorometric (Luminex xMAP)

Condiciones de envío

wet ice

Categorías relacionadas

Descripción general

MILLIPLEX® Rat Kidney Toxicity Bead Panels 1 & 2, coupled with the Luminex® xMAP®platform in a bead format, enables you to focus on discovery so you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, dramatically improving productivity.

Panel Type: Toxicity

Especificidad

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Aplicación

  • Analytes: Alpha-1 Acid Glycoprotein (AGP), Albumin, ß2M, Cystatin C, EGF, Lipocalin-2/NGAL
  • Recommended Sample type: urine
  • Recommended Sample dilution: 1:500
  • Assay Run Time: Overnight
  • Research Category: Toxicity

Características y beneficios

Design your multiplex kit by choosing available analytes within this panel.

Envase

Everything you need in a single kit.

Almacenamiento y estabilidad

Recommended storage for kit components is 2 - 8°C.

Otras notas

Sensitivity: See kit protocol for individual analytes sensitivities.

Información legal

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogramas

Skull and crossbonesEnvironment
GHS06,GHS09

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Michael J Coyne et al.
PloS one, 17(5), e0269085-e0269085 (2022-05-28)
Symmetric dimethylarginine (SDMA) is a serum biomarker of excretory renal function which consistently correlates with glomerular filtration rate (GFR) across multiple species including rats, dogs, and humans. In human and veterinary clinical settings SDMA demonstrates enhanced sensitivity for detection of
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Mónica Ríos-Silva et al.
Molecules (Basel, Switzerland), 24(1) (2018-12-26)
Capsaicin is an agonist of the transient receptor potential vanilloid type 1 (TRPV1) channel, which has been related to the pathophysiology of kidney disease secondary to diabetes. This study aimed to evaluate the chronic effect of capsaicin administration on biomarkers
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
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Nephrotoxicity Analysis with Kidney Toxicity Multiplex Assays | MILLIPLEX® Assays

Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.

Nephrotoxicity Analysis with Kidney Toxicity Multiplex Assays | MILLIPLEX® Assays

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