5.05024

Ibotenic Acid

• Sinónimos: Ibotenic Acid, 2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid, α-Amino-(3-hydroxy-5-isoxazolyl)acet­ic acid, Glutamate Receptor Agonist, Ibotenic acid
• Fórmula empírica (notación de Hill): C₅H₆N₂O₄
• Número de CAS: 2552-55-8
• Peso molecular: 158.11
• MDL number: MFCD00069294
• UNSPSC Code: 12352106
• NACRES: NA.77

Propiedades

• assay: ≥99% (HPLC)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: water: 10 mM
• storage temp.: −20°C
• InChI: 1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
• InChI key: IRJCBFDCFXCWGO-UHFFFAOYSA-N

Descripción

General description

A highly potent agonist of NMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts.

Warning

Toxicity: Regulatory Review (Z)

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Izquierdo, A., et al. 2013. J. Neurosci.33, 4105.
Rhodes, V., et al. 2013. J. Neurosci.33, 3380.
Yu, X., et al. 2012. Pharmacol. Biochem. & Beh.101, 479.
Albasser, M., et al. 2012. Beh. Neurosci.126, 659.
Eijkenboom, M., et al. 2000. Neurosci.101, 27.
Isacson, O., et al. 1984. Nature.311, 458.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable