1.00886

Ethyl 4-hydroxybenzoate sodium salt

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Sinónimos: Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt
• Fórmula empírica (notación de Hill): C₉H₉NaO₃
• Número de CAS: 35285-68-8
• Peso molecular: 188.16
• UNSPSC Code: 12352108
• EC Index Number: 252-487-6

Propiedades

• agency: BP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 10 (20 °C, 1 g/L in H₂O)
• bp: 297 °C/1013 hPa (free ester,decomposition)
• mp: >115 °C (free ester)
• transition temp: flash point 121 °C
• solubility: 1000 g/L
• application(s): liquid formulation; ophthalmics; pharmaceutical
• storage temp.: 15-25°C
• InChI: 1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1
• InChI key: QYNMSPKSYXPZHG-UHFFFAOYSA-M

Descripción

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 249.8 °F
• flash_point_c: 121 °C