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Merck
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Key Documents

07-614

Sigma-Aldrich

Anti-Surfactant Protein B Antibody

serum, Upstate®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

mouse ... Sftpd(20390)

Specificity

Surfactant Protein B

Immunogen

Purified human surfactant protein B

Application

Anti-Surfactant Protein B Antibody is an antibody against Surfactant Protein B for use in IH & WB.
Research Category
Metabolism
Research Sub Category
Ion & Transport Channels

Quality

routinely evaluated by immunoblot on human bronchiolar lavage fluid.

Target description

8kDa

Physical form

Serum
rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Yan Liu et al.
Molecular reproduction and development, 84(8), 668-674 (2017-05-18)
Respiratory distress is a major cause of mortality in cloned neonatal animals, but its pathogenesis remains poorly understood. Here, we used necropsy and histology procedures to evaluate the lungs of cloned neonatal bovines dying of respiratory distress, finding incomplete lung
Ralph Epaud et al.
American journal of respiratory cell and molecular biology, 28(3), 373-378 (2003-02-21)
Transgenic mice, in which the level of surfactant protein (SP)-B mature peptide varied 5.6-fold between SP-B(+/-) and SP-B-overexpressing lines (SP-B+/+/+), were used to test the hypothesis that SP-B protects against endotoxin-induced lung inflammation. Intratracheal administration of endotoxin resulted in significantly
L M Nogee et al.
American journal of respiratory and critical care medicine, 161(3 Pt 1), 973-981 (2000-03-11)
Inability to produce surfactant protein B (SP-B) causes fatal neonatal respiratory disease. A frame-shift mutation (121ins2) is the predominant but not exclusive cause of disease. To determine the range of mechanisms responsible for SP-B deficiency, both alleles from 32 affected
Lili Zhang et al.
Neoplasia (New York, N.Y.), 20(2), 207-217 (2018-01-15)
Risk stratification using molecular features could potentially help distinguish indolent from aggressive prostate cancer (PCa). Mutations in isocitrate dehydrogenase (IDH) acquire an abnormal enzymatic activity, resulting in the production of 2-hydroxyglutarate and alterations in cellular metabolism, histone modification, and DNA
Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.
Gregory, T J, et al.
The Journal of Clinical Investigation, 88, 1976-1981 (1991)

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