T-006

(±)-11-nor-9-Carboxy-Δ⁹-THC solution

100 μg/mL in methanol, ampule of 1 mL, Cerilliant^®

• Fórmula empírica (notación de Hill): C₂₁H₂₈O₄
• Número de CAS: 104874-50-2
• Peso molecular: 344.44
• Número CE: 200-659-6
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: certified reference material
• Nivel de calidad: 300
• Formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• drug control: psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• concentración: 100 μg/mL in methanol
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: cannabis testing; forensics and toxicology
• Formato: single component solution
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CCCCCc1cc(O)c2C3C=C(CCC3C(C)(C)Oc2c1)C(O)=O
• InChI: 1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)
• Clave InChI: YOVRGSHRZRJTLZ-UHFFFAOYSA-N

Descripción

Descripción general

11-nor-9-Carboxy-Δ⁹-THC, also known as THC acid, is the main secondary metabolite of Δ⁹-THC found in urine or blood of cannabis users. This certified reference solution is suitable as starting materials in the preparation of calibrators and controls for THC testing by GC/MS or LC/MS in forensic analysis, urine drug testing, or clinical toxicology.

Aplicación

• Development and Validation of LC-HRMS for Cannabinoids in Whole Blood: This study introduces a liquid chromatography high-resolution mass spectrometry (LC-HRMS) method for quantifying cannabinoids, demonstrating its application in determining recent cannabis use, highlighting the relevance of THC metabolites like (±)-11-nor-9-Carboxy-Δ⁹-THC as analytical standards (DeGregorio et al., 2020).
• Enhanced LC-MS-MS Technique for Distinguishing Tetrahydrocannabinol Isomers: Research focused on an improved LC-MS-MS method capable of distinguishing Δ8- and Δ9-tetrahydrocannabinol isomers in biological specimens, pertinent for forensic toxicology using standards such as (±)-11-nor-9-Carboxy-Δ⁹-THC (Reber et al., 2022).
• Toxicogenetic Analysis of Δ9-THC-metabolizing Enzymes: This study explores the metabolism of THC, providing insights into the toxicogenetics of cannabinoid-metabolizing enzymes, relevant for drug metabolism studies using (±)-11-nor-9-Carboxy-Δ⁹-THC as a reference material (Gasse et al., 2020).

Otras notas

Racemic mixture - not to be used for immunoassay

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225,H301 + H311 + H331,H370
• Consejos de prudencia: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órganos de actuación: Eyes,Central nervous system
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 49.5 °F - closed cup
• Punto de inflamabilidad (°C): 9.7 °C - closed cup