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LM1502

Avanti

17:0-20:4 PI

Avanti Research™ - A Croda Brand LM1502, methanol solution

Sinónimos:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)

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About This Item

Fórmula empírica (notación de Hill):
C46H84NO13P
Número de CAS:
1246304-59-5
Peso molecular:
890.13
Código UNSPSC:
12352211
NACRES:
NA.25

Formulario

methanol solution

envase

pkg of 1 × 1 mL (LM1502-1EA)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand LM1502

concentración

~10 μg/mL (Refer to C of A for lot specific concentration. )

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C46H81O13P.H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)58-38(37-57-60(54,55)59-46-44(52)42(50)41(49)43(51)45(46)53)36-56-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2;/h11,13,17,19,21,23,27,29,38,41-46,49-53H,3-10,12,14-16,18,20,

Clave InChI

AUAQSQQWFOADLK-AQBZCRPISA-N

Descripción general

Phosphatidylinositol (PI) is soluble in water and chloroform/methanol. It is commonly found in animal tissues and bacteria.

Aplicación

17:0-20:4 PI has been used as an internal standard for:
  • lipid extraction from isolated pure mitochondria by modified Bligh and Dyer method
  • lipid quantitation using liquid chromatography-mass spectrometry (LC-MS)
  • the analysis of phosphatidylinositol (PI) and phosphatidylinositol bisphosphates (PI(3,4)P2 and PI(4,5)P2) by high performance liquid chromatography-mass spectrometry (HPLC-MS)

Envase

2 mL Amber Glass Sealed Ampule (LM1502-1EA)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number

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Jiyuan Yang et al.
The Plant cell, 32(5), 1749-1767 (2020-03-15)
In plants, changes in cell size and shape during development fundamentally depend on the ability to synthesize and modify cell wall polysaccharides. The main classes of cell wall polysaccharides produced by terrestrial plants are cellulose, hemicelluloses, and pectins. Members of
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Mouhannad Malek et al.
Molecular cell, 68(3), 566-580 (2017-10-24)
The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P3. PI(3,4,5)P3 can be dephosphorylated by 3- or 5-phosphatases, the latter producing PI(3,4)P2. The PTEN tumor suppressor is thought
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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