A76109
3-Amino-1-propanesulfonic acid
97%
Sinónimos:
3APS, Homotaurine, Tramiprosate
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About This Item
Fórmula lineal:
H2N(CH2)3SO3H
Número de CAS:
Peso molecular:
139.17
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22
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Ensayo
97%
Formulario
solid
mp
293 °C (dec.) (lit.)
cadena SMILES
NCCCS(O)(=O)=O
InChI
1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
Clave InChI
SNKZJIOFVMKAOJ-UHFFFAOYSA-N
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Categorías relacionadas
Aplicación
Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA).
Código de clase de almacenamiento
13 - Non Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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Los clientes también vieron
D Saumier et al.
The journal of nutrition, health & aging, 13(9), 808-812 (2009-10-09)
Tramiprosate (homotaurine, ALZHEMEDTM) was recently investigated for its efficacy, safety and disease-modification effects in a Phase III clinical study in mild to moderate Alzheimer's disease (AD) patients (the Alphase study). The primary cognitive endpoint measure of that study was the
R Nageswara Rao et al.
Journal of pharmaceutical and biomedical analysis, 55(2), 282-287 (2011-02-18)
Alzheimer disease (AD) is characterized pathologically by extracellular amyloid deposits composed of amyloid β (Aβ) protein. A simple and rapid method using HPLC with fluorescence detector was developed and validated for determination of tramiprosate in rat plasma. Pre-column derivatization of
S Gauthier et al.
The journal of nutrition, health & aging, 13(6), 550-557 (2009-06-19)
The efficacy, safety and disease-modification of tramiprosate (homotaurine)were investigated in a recently completed large-scale Phase III clinical study in patients with mild to moderate Alzheimer's disease (AD), the Alphase study. Disease-modification was assessed using longitudinal volumetric MRI (vMRI) measurements of
J Y Wu et al.
Journal of biomedical science, 8(1), 96-103 (2001-02-15)
Acamprosate (AC), N-acetyl-homotaurine, has recently been introduced for treating alcohol craving and reducing relapses in weaned alcoholics. AC may exert its action through the taurine system rather than the glutamatergic or GABAergic system. This conclusion is based on the observations
P S Aisen et al.
Neurology, 67(10), 1757-1763 (2006-11-04)
As a potential disease-modifying treatment for Alzheimer disease (AD), 3-amino-1-propanesulfonic acid (3APS) is a compound that binds to amyloid beta (Abeta), a toxic protein known to aggregate, leading to amyloid plaque deposition in the brain. We assessed the safety, tolerability
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