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Merck

902268

Sigma-Aldrich

seMpai

Sinónimos:

DP3-Na, TokeOni analogue, water-soluble NIR emission luciferin analogue, 2-[(1E,3E)-6-[3-(dimethylamino)pyridine]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C15H16N3NaO2S
Peso molecular:
325.36
UNSPSC Code:
12352106
NACRES:
NA.23

description

Purity: mixture of D (80% min.) and L (20% max.) forms

form

powder

color

black to yellow-brown

storage temp.

−20°C

General description

2-[(1E,3E)-6-[3-(dimethylamino)pyridine]-1,3-butadien-1-yl]-4,5-dihydro-(4S)-4-thiazolecarboxylic acid sodium salt (DP3-Na) is a new NIR emission luciferin analog having luminescence peak at 670 ~ 680 nm with a peak range in the near-infrared (NIR) region with the enhanced solubility in water.
Luciferin is a generic term for the light-emitting compound found in organisms that generate bioluminescence.

Application

Applications:
  • Bioimaging
  • In vivo imaging

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging.
Saito R, et al.
Bulletin of the Chemical Society of Japan, 92(3), 182-8585 (2018)
Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging
Kiyama M, et al.
Tetrahedron, 74(6), 652- 660 (2018)
Visualization of activity-regulated BDNF expression in the living mouse brain using non-invasive near-infrared bioluminescence imaging.
Fukuchi M, et al.
Molecular Brain, 13(1), 122-122 (2020)
High Sensitivity In Vivo Imaging of Cancer Metastasis Using a Near-Infrared Luciferin Analogue seMpai
Nakayama J, et al.
International Journal of Molecular Sciences, 21(21), 7896-7896 (2020)

Artículos

Bioluminescence imaging (BLI) systems allows for high-sensitive and noninvasive monitoring of cell proliferation, activity of signaling pathways and protein-protein interactions in living tissues.

seMpai substrate is suitable for near-infrared BLI in biological experiments, offering high solubility for extended bioluminescent applications.

seMpai substrate is suitable for near-infrared BLI in biological experiments, offering high solubility for extended bioluminescent applications.

seMpai substrate is suitable for near-infrared BLI in biological experiments, offering high solubility for extended bioluminescent applications.

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