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Merck

767654

Sigma-Aldrich

cis-Dichlorobis(dimethyl sulfoxide)platinum(II)

97%

Sinónimos:

cis-Dichlorobis(dimethylsulfoxido)platinum(II), Pt(DMSO)2Cl2

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About This Item

Fórmula empírica (notación de Hill):
C4H12Cl2O2PtS2
Número de CAS:
Peso molecular:
422.25
MDL number:
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

solid

reaction suitability

core: platinum
reagent type: catalyst

mp

218-224 °C

SMILES string

Cl[Pt]Cl.CS(C)=O.CS(C)=O

InChI

1S/2C2H6OS.2ClH.Pt/c2*1-4(2)3;;;/h2*1-2H3;2*1H;/q;;;;+2/p-2

InChI key

KDADQDWVKZJTDQ-UHFFFAOYSA-L

General description

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) is a platinum complex used as a catalyst in various chemical reactions, including the methylation of polyfluorinated aryl imines and methane oxidation. It is identified as an effective C-F activation precatalyst.

Application

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) can be used as a:
  • Catalyst in the oleum-mediated (SO3-H2SO4) methane oxidation to form methyl bisulfate (MBS).
  • Precursor in the synthesis of cyclometalated complexes.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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L Türkeri et al.
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Osteosarcoma in adolescents and young adults: new developments and controversies. Thermal chemosensitization of cDDP-resistant cells.
A W Konings et al.
Cancer treatment and research, 62, 93-100 (1993-01-01)
A W Konings et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 9(4), 553-562 (1993-07-01)
cDDP-resistant Ehrlich ascites tumour (EAT) cells (ER cells) were tested for cellular content of total glutathione, heat sensitivity, cDDP sensitivity and synergistic effects of a combined treatment of heat and chemotherapy. In comparison with the non-resistant EAT cells (EN) the
J A Gondal et al.
European journal of cancer (Oxford, England : 1990), 29A(11), 1536-1542 (1993-01-01)
The systemic toxicity and efficacy of cisplatin (CDDP) were examined in vitro and in vivo. Procedures were performed before and after the antineoplastic agent was encapsulated into multilamellar liposomes (L-CDDP). In vitro cytotoxicity evaluation in L1210 murine leukaemia and NIH
H Nakagawa et al.
Journal of neuro-oncology, 16(1), 69-76 (1993-04-01)
Parenchymal brain tumors, which were metastases of primary lung cancer, were surgically removed from 25 patients. During the operation, patients were administered (intravenous or intracarotid) 100 mg/sq m of cis-diamminedichloroplatinum (CDDP) and postoperatively, they received intravenous CDDP at 3-month intervals

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