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543136

Sigma-Aldrich

Propargyl acrylate

98%

Sinónimos:

Acrylic acid propargyl ester

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About This Item

Fórmula lineal:
CH2=CHCO2CH2C≡CH
Número de CAS:
10477-47-1
Peso molecular:
110.11
EC Number:
233-975-8
MDL number:
MFCD00078451
UNSPSC Code:
12352100
PubChem Substance ID:
24878664
NACRES:
NA.22

assay

98%

contains

200 ppm BHT as inhibitor

refractive index

n20/D 1.447 (lit.)

bp

142-143 °C (lit.)

density

0.997 g/mL at 25 °C (lit.)

SMILES string

C=CC(=O)OCC#C

InChI

1S/C6H6O2/c1-3-5-8-6(7)4-2/h1,4H,2,5H2

InChI key

WPBNLDNIZUGLJL-UHFFFAOYSA-N

General description

Propargyl acrylate is a propargyl ester of acrylic acid. It participates in the preparation of lipid nanoparticles for use in siRNA delivery.

Application

Propargyl acrylate may be used to synthesize:
  • linear poly(N-isopropylacrylamide)(PNIPAM)
  • 1-[3-(2-methyl-2-dodecylsulfanylthiocarbonylsulfanylpropionyloxy)propyl]-1H-[1,2,3]triazol-4-ylmethyl acrylate, an acryloyl trithiocarbonate chain transfer agent
  • propranolol-imprinted core–shell nanoparticles (mipCS)

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

109.9 °F - closed cup

flash_point_c

43.3 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery.
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Proceedings of the National Academy of Sciences of the USA, 110(32), 12881-12886 (2013)
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Journal of separation science, 39(8), 1461-1470 (2016-02-26)
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