530301

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride

97%

• Sinónimos: 2-(Chloromethyl)-3,4-dimethoxypyridinium hydrochloride
• Fórmula empírica (notación de Hill): C₈H₁₁Cl₂NO₂
• Número de CAS: 72830-09-2
• Peso molecular: 224.08
• Beilstein/REAXYS Number: 5360726
• EC Number: 416-440-5
• MDL number: MFCD02181083
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877740
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 97%
• mp: 155 °C (dec.) (lit.)
• SMILES string: Cl[H].COc1ccnc(CCl)c1OC
• InChI: 1S/C8H10ClNO2.ClH/c1-11-7-3-4-10-6(5-9)8(7)12-2;/h3-4H,5H2,1-2H3;1H
• InChI key: YYRIKJFWBIEEDH-UHFFFAOYSA-N

Descripción

General description

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.

Application

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.

Información de seguridad

• pictograms: GHS08,GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302 + H312,H315,H317,H318,H373,H411
• pcodes: P273 - P280 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves