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Merck
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390593

Sigma-Aldrich

1-(1-Adamantyl)ethylamine hydrochloride

99%

Sinónimos:

α-Methyltricyclo[3.3.1.13,7]-decane-1-methanamine hydrochloride, Rimantadine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C12H21N · HCl
Número de CAS:
1501-84-4
Peso molecular:
215.76
MDL number:
MFCD00072023
UNSPSC Code:
12352100
PubChem Substance ID:
24864331
NACRES:
NA.22

assay

99%

mp

>300 °C (lit.)

SMILES string

Cl.C[C@H](N)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI

1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H/t8?,9-,10+,11-,12-;

InChI key

OZBDFBJXRJWNAV-MZHJCFSPSA-N

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Rafal M Pielak et al.
Structure (London, England : 1993), 19(11), 1655-1663 (2011-11-15)
The M2 channel of influenza A is a target of the adamantane family antiviral drugs. Two different drug-binding sites have been reported: one inside the pore, and the other is a lipid-facing pocket. A previous study showed that a chimera
Guang-Quan Wang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 98, 275-281 (2012-09-11)
Amantadine hydrochloride (AMA) and rimantadine hydrochloride (RIM) are non-fluorescent in aqueous solutions. This property makes their determination through direct fluorescent method difficult. The competing reactions and the supramolecular interaction mechanisms between the two drugs and coptisine (COP) as they fight
Tijana Ivanovic et al.
PloS one, 7(3), e31566-e31566 (2012-03-14)
M2 protein of influenza A viruses is a tetrameric transmembrane proton channel, which has essential functions both early and late in the virus infectious cycle. Previous studies of proton transport by M2 have been limited to measurements outside the context
Belen Puente et al.
Journal of chromatographic science, 49(10), 745-752 (2011-11-15)
A new HPLC procedure with precolumn derivatization and rimantadine as the internal standard for determining memantine, a candidate agent for the treatment of glaucoma in plasma and vitreous humour, has been developed and validated. Precolumn derivatization was performed with 9-fluorenylmethyl-chloroformate-chloride
Saumil Doshi et al.
The Journal of infectious diseases, 204(12), 1848-1856 (2011-10-21)
The 2009 influenza pandemic led to guidelines emphasizing antiviral treatment for all persons hospitalized with influenza, including pregnant women. We compared antiviral use among adults hospitalized with influenza before and during the pandemic. The Emerging Infections Program conducts active population-based
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