1118000

Chloroquine phosphate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Chloroquine diphosphate salt, N⁴-(7-Chloro-4-quinolinyl)-N¹,N¹-dimethyl-1,4-pentanediamine diphosphate salt
• Empirical Formula (Hill Notation): C₁₈H₂₆ClN₃ · 2H₃PO₄
• CAS Number: 50-63-5
• Molecular Weight: 515.86
• Beilstein: 4223142
• MDL number: MFCD00069852
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749320
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• Agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: chloroquine
• form: powder
• packaging: pkg of 500 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: yellow
• pH: 3.5-4.5 (10% in aqueous solution, pH <6.0)
• mp: 200 °C (dec.) (lit.)
• solubility: water: 50 g/L; benzene: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
• InChI key: QKICWELGRMTQCR-UHFFFAOYSA-N

Description

General description

Chloroquine Phosphate is a salt of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Application

Chloroquine phosphate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Amodiaquine Hydrochloride
• Amodiaquine Hydrochloride Tablets
• Chloroquine
• Chloroquine Phosphate
• Chloroquine Phosphate Compounded Oral Suspension
• Chloroquine Phosphate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable