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X6000

Sigma-Aldrich

Xylometazoline hydrochloride

Synonym(s):

2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2 · HCl
CAS Number:
1218-35-5
Molecular Weight:
280.84
EC Number:
214-936-4
MDL number:
MFCD00238707
UNSPSC Code:
41116107
PubChem Substance ID:
24278781
NACRES:
NA.77

Quality Level

200

originator

Novartis

SMILES string

CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl

InChI

1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H

InChI key

YGWFCQYETHJKNX-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

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Biochem/physiol Actions

α-adrenoceptor agonist; imidazoline binding site ligand.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Prasun Mishra et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(1), 117-121 (2012-03-20)
During nasal endoscopy it is essential to have proper visualization of structures with minimal discomfort to patient and surgeon. For this it is essential that the nose is well prepared before the procedure. The main objective of the study is
Daniela Leupold et al.
The neurologist, 17(1), 41-43 (2010-12-31)
substance abuse is an important cause of ischemic stroke in the young. This includes over-the-counter dietary supplements and cough and cold remedies, which were reported to be an independent risk factor for hemorrhagic stroke. this article describes a young male
Catherine E Rennie et al.
International forum of allergy & rhinology, 1(2), 128-135 (2012-01-31)
This study quantifies the time-varying flow rate during inspiration at rest and in sniffing, both predecongestion and postdecongestion. It aims to provide a better understanding of nasal airflow mechanics, for application to the physiological modeling of nasal respiration and to
Jacek Sein Anand et al.
Przeglad lekarski, 66(6), 290-292 (2009-10-01)
The aim of our study was to present cases of misuse of different substances theoretically without abuse potential. In the last few years such behavior became an increasing problem in toxicological and emergency units. Lack of typical signs of intoxication
Nigel K F Koo Ng et al.
Orbit (Amsterdam, Netherlands), 29(6), 346-347 (2010-12-17)
We report a case of unilateral mydriasis following nasal electrocautery presumed to be the result of retrograde flow of adrenaline and/or xylometazoline hydrochloride (Otrivine) through the nasolacrimal duct into the eye. We review the literature and highlight the importance of
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