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T3384

Sigma-Aldrich

L-Tyrosine β-naphthylamide

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C19H18N2O2
CAS Number:
4357-95-3
Molecular Weight:
306.36
EC Number:
224-432-6
MDL number:
MFCD00046458
UNSPSC Code:
12352209
PubChem Substance ID:
24900136
NACRES:
NA.26

product name

L-Tyrosine β-naphthylamide,

Assay

≥98% (TLC)

Quality Level

200

form

powder

color

white to off-white

storage temp.

−20°C

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(=O)Nc2ccc3ccccc3c2

InChI

1S/C19H18N2O2/c20-18(11-13-5-9-17(22)10-6-13)19(23)21-16-8-7-14-3-1-2-4-15(14)12-16/h1-10,12,18,22H,11,20H2,(H,21,23)/t18-/m0/s1

InChI key

BZBYYTSHGRKCJJ-SFHVURJKSA-N

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P281

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J Negrel et al.
Phytochemistry, 56(6), 523-527 (2001-04-03)
L-Tyrosine beta-naphthylamide, a synthetic substrate designed to measure tyrosine aminopeptidase activity, is a potent inhibitor of hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) purified from elicited tobacco cell-suspension cultures. The inhibition is competitive, with the inhibitor binding reversibly to the tyramine binding site of
J M de Gandarias et al.
Life sciences, 59(13), 1097-1101 (1996-01-01)
Puromycin sensitive and insensitive membrane-bound aminopeptidase activity levels during the estrous cycle in several brain areas have been described in this research. We have found the highest aminopeptidase M activity levels during the proetrous stage in the hypothalamus, the amygdala
J M de Gandarias et al.
Arzneimittel-Forschung, 49(10), 816-819 (1999-11-11)
Lithium (CAS 7439-93-2) is being utilized widely for the treatment of manic-depressive illness. However, the neurochemical mechanism of the ion action still remains relatively obscure. In the present work, the effect of acute lithium administration on soluble and membrane-bound enkephalin-degrading

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