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Key Documents

SML0518

Sigma-Aldrich

NSC405020

≥98% (HPLC)

Synonym(s):

3,4-Dichloro-N-(1-methylbutyl)-benzamide, 3,4-Dichloro-N-(pentan-2-yl)benzamide, NSC 405020

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About This Item

Empirical Formula (Hill Notation):
C12H15Cl2NO
CAS Number:
Molecular Weight:
260.16
UNSPSC Code:
12352200
NACRES:
NA.77

Pricing and availability is not currently available.

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

room temp

InChI

1S/C12H15Cl2NO/c1-3-4-8(2)15-12(16)9-5-6-10(13)11(14)7-9/h5-8H,3-4H2,1-2H3,(H,15,16)

InChI key

ARDYECYBETXQFD-UHFFFAOYSA-N

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This Item
GF43925924GF79186348GF98944958
form

wire

form

wire

form

wire

form

wire

L × diam.

0.5 m × 0.8 mm

L × diam.

1 m × 0.8 mm

L × diam.

10 m × 0.8 mm

L × diam.

-

Biochem/physiol Actions

NSC405020 is a PEX inhibitor targeting the PEX domain of MT1-MMP that repressed tumor growth and caused a fibrotic DPEX-like tumor phenotype in vivo. NSC405020 does not inhibit the catalytic activity of MMP-2.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Laura Rolland et al.
    Journal of molecular cell biology (2022-10-23)
    Understanding how certain animals are capable of regenerating their hearts will provide much needed insights into how this process can be induced in humans in order to reverse the damage caused by myocardial infarction. Currently, it is becoming increasingly evident

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