SAB4500895

Anti-ATF5 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): ATF5, Activating transcription factor 5, Cyclic AMP-dependent transcription factor ATF-5, Transcription factor ATFx, cAMP-dependent transcription factor ATF-5
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 30 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; western blot: 1:500-1:1000
• NCBI accession no.: Q9Y2D1
• UniProt accession no.: Q9Y2D1
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ATF5(22809)

Description

General description

Activating transcription factor 5 (ATF5) belongs to the ATF/cAMP response element-binding protein family. It is an anti-apoptotic protein that has 282 amino acids and is located on human chromosome 19q13. It is expressed in various cancers like prostate, rectal, colon, endometrium, breast, ovary, pancreas, gastric etc.

Anti-ATF5 Antibody detects endogenous levels of total ATF5 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human ATF5.

Immunogen Range: 221-270

Biochem/physiol Actions

Activating transcription factor 5 (ATF5) participates in metabolite homeostasis, cellular proliferation, differentiation, apoptosis and regulation of the cell cycle. It controls neural progenitor cell and adipose-derived stem cell differentiation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable