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L6146

Sigma-Aldrich

Lugol solution

Synonym(s):

Iodine/Potassium iodide solution

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About This Item

UNSPSC Code:
12161900
NACRES:
NA.25
Pricing and availability is not currently available.

General description

Lugol solution is comprised of aqueous potassium iodide plus iodine. [1]

Application

Lugol solution has been used in a study to assess narrow-band imaging without image magnification for detecting high-grade dysplasia and intramucosal esophageal squamous cell carcinoma. [2] It has also been used in a study to determine its benefit in aiding detection of the presence and spread of small squamous cell carcinomas of the esophagus. [3]

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7251
BCCK7440
BCCH5982
BCCG9986
BCCG9987

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Erica L Clinkenbeard et al.
JCI insight, 4(4) (2019-03-05)
The phosphaturic hormone FGF23 is elevated in chronic kidney disease (CKD). The risk of premature death is substantially higher in the CKD patient population, with cardiovascular disease (CVD) as the leading mortality cause at all stages of CKD. Elevated FGF23
K Sugimachi et al.
Gastrointestinal endoscopy, 38(6), 657-661 (1992-11-01)
Small esophageal lesions, particularly intraepithelial cancers, are extremely difficult to detect. We used Lugol's iodine solution with panendoscopic examination to detect the presence and spread of small squamous cell carcinomas of the esophagus. Serial histologic specimens of the surgically removed
Michèle G DuVal et al.
PloS one, 9(2), e89183-e89183 (2014-03-04)
Mutation of Glass bottom boat, the Drosophila homologue of the bone morphogenetic protein or growth/differentiation factor (BMP/GDF) family of genes in vertebrates, has been shown to disrupt development of neuromuscular junctions (NMJ). Here we tested whether this same conclusion can
Karl Degenhardt et al.
Circulation. Cardiovascular imaging, 3(3), 314-322 (2010-03-02)
Microcomputed tomography (micro-CT) has been used extensively in research to generate high-resolution 3D images of calcified tissues in small animals nondestructively. It has been especially useful for the characterization of skeletal mutations but limited in its utility for the analysis
Jason B Thomas et al.
BMC plant biology, 17(1), 201-201 (2017-11-16)
Pennycress [Thlaspi arvense L (Brassicaceae)] is being domesticated as a renewable biodiesel feedstock that also provides crucial ecosystems services, including as a nutritional resource for pollinators. However, its flowers produce significantly less nectar than other crop relatives in the Brassicaceae.
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Lugol solution, L6146と32922との違いは何ですか。

    1 answer

    1. Both products are formulated to contain approximately 0.35% Iodine and 0.70% Potassium Iodide. While the concentration of L6146 is a bit higher at 0.37% Iodine and 0.74% Potassium Iodide, there is no functional difference between these two products. The formulations are typical for use in microscopy. The L6146 was originally a Sigma brand product while the 62650 was originally a Fluka brand product. Both now fall under the Sigma-Aldrich brand of products. The L6146 is tested for appearance and density, however, the 62650 has additional titration testing done to verify the concentration of each component. See the links below for a sample Certificate of Analysis for each product:

      L6146
      https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF735903.pdf
      62650
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/32922-BULKBCBZ9559.pdf

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