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F5379

Sigma-Aldrich

Fucosterol

≥93%, powder, antioxidant

Synonym(s):

3β-Hydroxy-5,24(28)-stigmastadiene, 5,24(28)-Stigmastadien-3β-ol

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About This Item

Empirical Formula (Hill Notation):
C29H48O
CAS Number:
Molecular Weight:
412.69
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.77

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product name

Fucosterol, ≥93%

Quality Level

Assay

≥93%

storage temp.

2-8°C

SMILES string

C\C=C(/CC[C@H](C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C

InChI

1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h7,10,19-20,23-27,30H,8-9,11-18H2,1-6H3/b21-7+

InChI key

OSELKOCHBMDKEJ-QPSGOUHRSA-N

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This Item
SAB4600179SAB4600127SAB4600467
species reactivity

chicken

species reactivity

chicken

species reactivity

chicken

species reactivity

guinea pig

biological source

goat

biological source

goat

biological source

donkey

biological source

donkey

technique(s)

flow cytometry: 1-10 μg/mL, immunohistochemistry: suitable, indirect immunofluorescence: 1-10 μg/mL, immunocytochemistry: suitable, western blot: suitable, indirect ELISA: suitable

technique(s)

flow cytometry: 1-10 μg/mL, immunocytochemistry: suitable, immunohistochemistry: suitable, indirect immunofluorescence: 1-10 μg/mL

technique(s)

flow cytometry: 1-10 μg/mL, immunocytochemistry: suitable, immunohistochemistry: suitable, indirect immunofluorescence: 1-10 μg/mL

technique(s)

flow cytometry: 1-10 μg/mL, immunocytochemistry: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, indirect immunofluorescence: 1-10 μg/mL, western blot: suitable

conjugate

CF 405M conjugate

conjugate

CF 647 conjugate

conjugate

CF 633 conjugate

conjugate

CF 405M conjugate

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

General description

Fucosterol is a phytosterol[1] abundantly present in algae, Ecklonia arborea and Silvetia compressa.[2]

Application

Fucosterol has been used:
  • as an environmental contaminant to study its effect on morphological development in growing zebrafish embryos and larvae[3]
  • to study its anxiolytic effects in mice[1]
  • as an external standard to analyze sterols in seaweed samples[2]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Customers Also Viewed

    J H Sheu et al.
    Journal of natural products, 62(2), 224-227 (1999-03-17)
    Fucosterol (1), 24xi-hydroperoxy-24-vinylcholesterol (2), 29-hydroperoxystigmasta-5,24(28)-dien-3beta-ol (3), 24-ethylcholesta-4,24(28)-dien-3-one (4), 24xi-hydroperoxy-24-ethylcholesta-4,28(29)-dien-3-one (5), 24-ethylcholesta-4,24(28)-dien-3,6-dione (6), 24xi-hydroperoxy-24-ethylcholesta-4,28(29)-dien-3,6-di one (7), 6beta-hydroxy-24-ethylcholesta-4,24(28)-dien-3-one (8), and 24xi-hydroperoxy-6beta-hydroxy-24-ethylcholesta-4,28(2 9)-dien-3-one (9) were isolated from the marine brown alga Turbinaria conoides. The structures of these compounds were established by spectral analysis.
    M Shimonaka et al.
    Thrombosis research, 36(3), 217-222 (1984-11-01)
    In a previous study(1), it was demonstrated that one of phytosterols, sitosterol, has an ability to increase the intracellular and extracellular activities of plasminogen activator in cultured endothelial cells and that other steroids including cholesterol, 5-androsten-3 beta-ol, stigmasterol, 20(R)-propyl-5-pregnen-3 beta-ol
    G V Vahouny et al.
    The American journal of clinical nutrition, 37(5), 805-809 (1983-05-01)
    Studies have been conducted on the lymphatic absorption of sitosterol (24 alpha-ethyl cholesterol), stigmasterol (delta 22, 24 alpha-ethyl cholesterol), and fucosterol (24-ethylidine cholesterol) when administered intragastrically to rats. In addition, the effect of each sterol on absorption of endogenous cholesterol
    I Ikeda et al.
    Journal of lipid research, 29(12), 1573-1582 (1988-12-01)
    The extent and site(s) of inhibition of cholesterol absorption by plant sterols, sitosterol and fucosterol, were studied in rats. The intragastric administration of a single emulsified lipid meal containing 25 mg [3H]cholesterol and 25 mg of either sitosterol or fucosterol
    Christian Galasso et al.
    Nutrients, 11(6) (2019-05-31)
    Epidemiological studies are providing strong evidence on beneficial health effects from dietary measures, leading scientists to actively investigate which foods and which specific agents in the diet can prevent diseases. Public health officers and medical experts should collaborate toward the

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