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Merck

D8161

Sigma-Aldrich

1,4-Dithioerythritol

BioReagent, for molecular biology, ≥99.0%

Synonym(s):

erythro-1,4-Dimercapto-2,3-butanediol, erythro-2,3-Dihydroxy-1,4-butanedithiol, Cleland’s reagent, DTE

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100 ML
€28.80

€28.80


Availability

Estimated to ship onFebruary 26, 2025


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100 ML
€28.80

About This Item

Linear Formula:
HSCH2CH(OH)CH(OH)CH2SH
CAS Number:
Molecular Weight:
154.25
Beilstein:
1719756
EC Number:
MDL number:
UNSPSC Code:
12161504
PubChem Substance ID:
NACRES:
NA.31

€28.80


Availability

Estimated to ship onFebruary 26, 2025


To order products, please contact your local dealer.

grade

for molecular biology

Quality Level

product line

BioReagent

Assay

≥99.0%

form

powder

reaction suitability

reagent type: reductant

pH

4.5-6.5 (25 °C, 15.4 g/L)

mp

82-84 °C (lit.)

solubility

water: 50 mg/mL

foreign activity

DNase, Exonuclease detection, RNase, and protease, none detected

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1 of 4

This Item
W332518328154493864
refractive index

n20/D 1.509 (lit.)

refractive index

n20/D 1.509 (lit.)

refractive index

-

refractive index

-

density

1.013 g/mL at 25 °C (lit.)

density

1.013 g/mL at 25 °C (lit.)

density

-

density

-

form

liquid

form

-

form

solid

form

-

bp

166-167 °C/717 mmHg (lit.)

bp

166-167 °C/717 mmHg (lit.)

bp

-

bp

-

Application

Reagent for maintaining −SH groups in the reduced state; quantitatively reduces disulfides.
reducing reagent

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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I Fialka et al.
Electrophoresis, 18(14), 2582-2590 (1998-04-04)
Protein targeting and sorting is accomplished by complex vesicular transport processes that are tightly regulated within a cell. This is especially important for epithelial cells because correct delivery of newly synthesized proteins as well as recycling and sorting of internalized
Ta-Lun Kao et al.
Theranostics, 8(10), 2672-2682 (2018-05-19)
Background and Aims: Improving liver regeneration (LR) capacity and thereby liver function reserve is a critical bridging strategy for managing liver failure patients. Since estrogen signaling may participate in LR, our aim was to characterize the roles of ERα and
C Pasquali et al.
Electrophoresis, 18(14), 2573-2581 (1998-04-04)
Electrophoretic techniques, and especially two-dimensional gel electrophoresis (2-DE), have provided an indispensable set of tools for the separation of complex protein mixtures as well as for the identification of protein-protein interactions. Nevertheless, after its introduction more than twenty years ago
Yang-Rae Kim et al.
ACS applied materials & interfaces, 2(1), 292-295 (2010-04-02)
A strategy for the rational design of a novel colorimetric sensor based on dithioerythritol-modified gold nanoparticles for the selective recognition of Hg2+ in aqueous media is presented. This approach relies on the combination of gold nanoparticles with Hg2+ through sulfur-Hg2+-sulfur
András Kolozsi et al.
Inorganic chemistry, 47(9), 3832-3840 (2008-04-03)
The aqueous solutions of arsenous acid with the meso and racemic forms of 1,4-dithiol-butane-2,3-diol, namely, dithioerythritol (dte) and dithiothreitol (dtt), respectively, were titrated pH-metrically in different molar ratios. The p K a values determined for As(OH) 3, and dtt were

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