75762
3-Deoxyglucosone
≥75% (TLC)
Synonym(s):
3-Deoxy-D-erythro-hexosulose
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About This Item
Recommended Products
Quality Level
Assay
≥75% (TLC)
form
solid
color
faintly yellow to orange
storage temp.
room temp
SMILES string
OC[C@H]1OC(O)C(=O)C[C@@H]1O
InChI
1S/C6H10O5/c7-2-5-3(8)1-4(9)6(10)11-5/h3,5-8,10H,1-2H2/t3-,5+,6?/m0/s1
InChI key
UHPMJDGOAZMIID-OPAZFOKUSA-N
Application
3-Deoxyglucosone is used as a reference for the analysis and detection of glucose degradation products, glycating agents, generated by processes such as heat sterilization.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Caatje Y le Poole et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 32(1), 45-54 (2011-06-03)
Standard peritoneal dialysis (PD) solutions contain high levels of glucose and glucose degradation products (GDPs), both contributing to the formation of advanced glycation end products (AGEs). We studied the contribution to plasma GDP and AGE levels of 2 PD regimens
Julia Degen et al.
Journal of agricultural and food chemistry, 60(28), 7071-7079 (2012-06-26)
1,2-Dicarbonyl compounds, formed from carbohydrates during thermal processing in the course of caramelization and Maillard reactions, are intensively discussed as precursors for advanced glycation endproducts in foods and in vivo. To obtain information about the uptake of individual compounds with
Stefan Mittelmaier et al.
Analytical chemistry, 83(24), 9660-9668 (2011-11-16)
The use of advanced glycation end-products (AGEs) as biomarkers for diagnosis and clinical studies is still hampered by insufficient knowledge on clinically relevant structures formed from precursors associated with defined disease states. The present study conducted untargeted analysis of the
Lian Engelen et al.
European journal of endocrinology, 164(3), 371-379 (2011-01-06)
Metformin has been reported to reduce α-dicarbonyls, which are known to contribute to diabetic complications. It is unclear whether this is due to direct quenching of α-dicarbonyls or to an improvement in glycemic control. We therefore compared the effects of
Alberto Ortiz et al.
Current medicinal chemistry, 13(22), 2695-2702 (2006-10-05)
Breakdown of glucose under physiological conditions gives rise to glucose degradation products (GDPs). GDPs are also formed during heat sterilization of glucose-containing peritoneal dialysis fluids (PD-fluids). In PD-fluids GDPs have been shown in many different in vitro assays to be
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