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19710

Sigma-Aldrich

L-2-Phosphoglyceric acid disodium salt hydrate

≥80% (CE)

Synonym(s):

L-Glycerate 2-phosphate disodium salt, Disodium L-2-phosphoglycerate

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About This Item

Empirical Formula (Hill Notation):
C3H5Na2O7P · xH2O
CAS Number:
23295-92-3
Molecular Weight:
230.02 (anhydrous basis)
UNSPSC Code:
12352204
PubChem Substance ID:
329751938
NACRES:
NA.28

Quality Level

100

Assay

≥80% (CE)

form

solid

impurities

≤0.2% P(i)
≤35% water

color

white to faintly brown

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].OC[C@H](OP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na.H2O/c4-1-2(3(5)6)10-11(7,8)9;;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;;1H2/q;2*+1;/p-2/t2-;;;/m0.../s1

InChI key

VQNAIZNPWBGZNQ-SQGDDOFFSA-L

Biochem/physiol Actions

Opposite enantiomer to the standard configuration found in glycolysis/gluconeogenesis.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M J Jedrzejas et al.
The Journal of biological chemistry, 275(30), 23146-23153 (2000-04-15)
The structure of the complex between the 2, 3-diphosphoglycerate-independent phosphoglycerate mutase (iPGM) from Bacillus stearothermophilus and its 3-phosphoglycerate substrate has recently been solved, and analysis of this structure allowed formulation of a mechanism for iPGM catalysis. In order to obtain
Bo Liu et al.
Extremophiles : life under extreme conditions, 11(5), 733-739 (2007-06-15)
A glycerate kinase (GK) gene (PH0495) from the hyperthermophilic archaeon Pyrococcus horikoshii, was cloned and expressed in Escherichia coli. The recombinant protein was purified to homogeneity by affinity chromatography and ion exchange chromatography. The enzyme was likely a homodimer based
Keri Lyn Ross et al.
Analytical chemistry, 81(10), 4021-4026 (2009-04-10)
A method has been developed for rapid quantification of nine glycolytic intermediates using ultraperformance liquid chromatography/electrospray-tandem mass spectrometry (UPLC/ESI-MS/MS) to monitor the metabolism of glucose during microbial fermentation. Because comprehensive chromatographic separation is not required, analysis time is significantly less
Matthias Reher et al.
FEMS microbiology letters, 259(1), 113-119 (2006-05-11)
Picrophilus torridus has been shown to degrade glucose via a nonphosphorylative Entner-Doudoroff (ED) pathway. Here we report the characterization of a key enzyme of this pathway, glycerate kinase (2-phosphoglycerate forming). The enzyme was purified 5,100-fold to homogeneity. The 95 kDa
Zhiru Li et al.
Veterinary parasitology, 176(4), 350-356 (2011-02-18)
Drug treatments for heartworm disease have not changed significantly in the last decade. Due to concerns about possible drug resistance and their lower efficacy against adult worms, there is a need for the development of new antifilarial drug therapies. The
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