PHR1280
Xylitol
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Xylite
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About This Item
Linear Formula:
HOCH2[CH(OH)]3CH2OH
CAS Number:
Molecular Weight:
152.15
Beilstein:
1720523
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to Ph. Eur. X0080000
traceable to USP 1720600
API family
xylitol
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
94-97 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
OC[C@@H](O)[C@H](O)[C@@H](O)CO
InChI
1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+
InChI key
HEBKCHPVOIAQTA-SCDXWVJYSA-N
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General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Xylitol is a naturally occurring polyhydric sugar alcohol with high sweetening power and anticariogenic properties.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Xylitol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by capillary isotachophoresis.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC4431 in the slot below. This is an example certificate only and may not be the lot that you receive.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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As Saccharomyces cerevisiae cannot utilize xylose as a carbon source, expression of XYL1 coding for xylose reductase (XR) from Scheffersomyces (Pichia) stipitis enabled production of xylitol from xylose with a high yield. However, insufficient supply of NAD(P)H for XR and
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Protocols
Separation of Maltotriose; Maltose; Xylitol
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