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P1847

Sigma-Aldrich

Potassium gluconate

97.0-103.0% dry basis, meets USP testing specifications

Synonym(s):

Potassium D-gluconate, 2,3,4,5,6-Pentahydroxycaproic acid potassium salt, D-Gluconic acid potassium salt

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About This Item

Empirical Formula (Hill Notation):
C6H11KO7
CAS Number:
Molecular Weight:
234.25
Beilstein:
3919448
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

grade

anhydrous

Quality Level

Agency

USP/NF
meets USP testing specifications

Assay

97.0-103.0% dry basis

form

powder

impurities

≥1.0 % (v/v) reducing substances

color

white

mp

183 °C (dec.) (lit.)

solubility

water: soluble

application(s)

pharmaceutical (small molecule)

SMILES string

[K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

HLCFGWHYROZGBI-JJKGCWMISA-M

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Application

Potassium gluconate has been used as:
  • a component in intracellular solution (1x) for electrophysiology recordings in cultured neurons
  • as a component of solution for electroporation of neurons
  • in the preparation of intracellular pipette solution

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Optogenetic stimulation and recording of primary cultured neurons with spatiotemporal control
Barral J and Reyes AD
Bio-protocol, 7(12) (2017)
In vivo functional mapping of a cortical column at single-neuron resolution
Tischbirek CH, et al.
Cell Reports, 27(5), 1319-1326 (2019)
Assembly and operation of the autopatcher for automated intracellular neural recording in vivo
Kodandaramaiah SB, et al.
Nature Protocols, 11(4), 634-634 (2016)
Carsten H Tischbirek et al.
Cell reports, 27(5), 1319-1326 (2019-05-03)
The cerebral cortex is organized in vertical columns that contain neurons with similar functions. The cellular micro-architecture of such columns is an essential determinant of brain dynamics and cortical information processing. However, a detailed understanding of columns is incomplete, even
Esther Krook-Magnuson et al.
The Journal of physiology, 593(10), 2379-2388 (2015-03-11)
The dentate gyrus is a region subject to intense study in epilepsy because of its posited role as a 'gate', acting to inhibit overexcitation in the hippocampal circuitry through its unique synaptic, cellular and network properties that result in relatively

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