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N6142

Supelco

Nabumetone

analytical standard

Synonym(s):

4-(6-Methoxy-2-naphthyl)-2-butanone

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About This Item

Empirical Formula (Hill Notation):
C15H16O2
CAS Number:
42924-53-8
Molecular Weight:
228.29
MDL number:
MFCD00079518
UNSPSC Code:
41116107
PubChem Substance ID:
329818660
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

COc1ccc2cc(CCC(C)=O)ccc2c1

InChI

1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

InChI key

BLXXJMDCKKHMKV-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Nonselective non-steroidal anti-inflammatory drug (NSAID)

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN3727
MKCG6105
MKCD9732
MKBZ6732V
MKBT7117V

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Recent breakthroughs in creating induced pluripotent stem cells (iPSCs) provide alternative means to obtain embryonic stem-like cells without destroying embryos by introducing four reprogramming factors (Oct3/4, Sox2, and Klf4/c-Myc or Nanog/Lin28) into somatic cells. iPSCs are versatile tools for investigating
Markku Kerola et al.
Basic & clinical pharmacology & toxicology, 104(1), 17-21 (2009-01-21)
: The beneficial actions of non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with inhibition of cyclooxygenase-2 (COX-2), whereas some of their adverse effects are associated mainly with inhibition of COX-1. Selective COX-2 inhibitors reduce the risk of gastrointestinal adverse events
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