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Merck

H8000

Sigma-Aldrich

L-Histidine

≥99% (TLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
Beilstein:
84088
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

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product name

L-Histidine, ReagentPlus®, ≥99% (TLC)

Quality Level

product line

ReagentPlus®

Assay

≥99% (TLC)

form

powder

color

white to off-white

mp

282 °C (dec.) (lit.)

solubility

0.5 M HCl: 50 mg/mL

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

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Application

L-histidine has been used for the selection of transformed cells.[1] It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.[2]

Biochem/physiol Actions

L-Histidine is an essential amino acid.[3] It binds to metal ions and may aid in the transport of copper.[4] Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.[5]
Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity
Eleni K
Scientific Reports (2017)
Roger L. Lundblad
Chemical Reagents for Protein Modification (2014)
Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Alexandra m
Bio-protocol (2017)
Catherine Collin, Masaru Minami, Hasan Parvez, Hideya Saito, Simone Parvez, Qureshi, Claude Reiss
Advances in Neurochemistry (2005)
Kakulavarapu V Rama Rao et al.
The American journal of pathology, 176(3), 1400-1408 (2010-01-16)
Brain edema and the associated increase in intracranial pressure are potentially lethal complications of acute liver failure (ALF). Astrocyte swelling (cytotoxic edema) represents a significant component of the brain edema in ALF, and elevated blood and brain ammonia levels have

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Chromatograms

application for HPLC

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