F8798

Folic acid

meets USP testing specifications

• Synonym(s): PteGlu, Pteroyl-L-glutamic acid, Vitamin M
• Empirical Formula (Hill Notation): C₁₉H₁₉N₇O₆
• CAS Number: 59-30-3
• Molecular Weight: 441.40
• Beilstein: 100781
• EC Number: 200-419-0
• MDL number: MFCD00079305
• UNSPSC Code: 12352100
• eCl@ss: 34058014
• PubChem Substance ID: 24894977
• NACRES: NA.21

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Agency: USP/NF; meets USP testing specifications
• Assay: 97.0-102.0% dry basis
• form: solid
• color: yellow
• mp: >285 °C
• application(s): cell analysis; pharmaceutical (small molecule)
• functional group: amide; amine; carboxylic acid
• SMILES string: NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O
• InChI: 1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChI key: OVBPIULPVIDEAO-LBPRGKRZSA-N

Description

General description

Folic acid, also known as pteroyl-L-glutamic acid, belongs to the vitamin B group. The conformational analysis of folic acid in the solution has been reported based on nuclear magnetic resonance (NMR) and theoretical calculations. The reaction kinetics of the photodecomposition under ultraviolet radiation has been investigated. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Application

Folic acid has been used in a study to investigate its protective effects against the toxicity caused by valproic acid (VPA) on maternal liver tissue. It has also been used as standard for the quantification of plasma folic acid by reversed-phase HPLC.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves