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Key Documents

E9876

Supelco

Ethylhydrocupreine hydrochloride

analytical standard

Synonym(s):

Optochin

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About This Item

Empirical Formula (Hill Notation):
C21H28N2O2 · HCl
CAS Number:
Molecular Weight:
376.92
Beilstein:
4055970
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34

InChI

1S/C21H28N2O2.ClH/c1-3-14-13-23-10-8-15(14)11-20(23)21(24)17-7-9-22-19-6-5-16(25-4-2)12-18(17)19;/h5-7,9,12,14-15,20-21,24H,3-4,8,10-11,13H2,1-2H3;1H/t14-,15-,20-,21+;/m0./s1

InChI key

QNRATNLHPGXHMA-XZHTYLCXSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sensitive and specific reagent for the identification of Streptococcus pneumoniae.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Rehab H Bahy et al.
Jundishapur journal of microbiology, 9(4), e30708-e30708 (2016-06-16)
Streptococcus pneumoniae is still one of the major causes of morbidity and mortality worldwide. The prevalent serotype distribution had shown variation along different studies conducted at different time intervals. In order to efficiently assess the epidemiology of the diseases for
Kyung Hyo Kim et al.
Clinical and diagnostic laboratory immunology, 10(4), 616-621 (2003-07-11)
For evaluating pneumococcal vaccines, the opsonophagocytic killing assay (OPKA) is useful as a supplement to the pneumococcal antibody enzyme-linked immunosorbent assay (ELISA). However, evaluations of pneumococcal vaccines require the determination of antibody responses to 7 to 11 serotypes, and the
Paulo R Cortes et al.
The Journal of antimicrobial chemotherapy, 62(5), 973-977 (2008-08-08)
The aim of this work was to study the effect of subinhibitory concentrations of penicillin, chloramphenicol and erythromycin on the mutation rate of Streptococcus pneumoniae. The mutation rate to rifampicin and optochin resistance was estimated using fluctuation analysis in three
Luz Balsalobre et al.
Antimicrobial agents and chemotherapy, 57(1), 254-260 (2012-11-02)
Fourteen fluoroquinolone-resistant streptococcal isolates with recombinant DNA topoisomerase genes, preliminarily identified as pneumococci, were further characterized using phenotypic and genotypic approaches. Phenotypic tests classified them as atypical pneumococci. Phylogenetic relationships were analyzed by using the sequences of seven housekeeping alleles
Tarja Kaijalainen et al.
Journal of microbiological methods, 51(1), 111-118 (2002-06-19)
To find reliable methods able to identify the "difficult" Streptococcus pneumoniae isolates, an in-house polymerase chain reaction (PCR) for pneumolysin gene (Ply-PCR) and a commercial RNA hybridisation test (AccuProbe) were evaluated. Selected isolates of suspected pneumococci, sent for confirmation of

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