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D9516

Supelco

Diaveridine

analytical standard, ≥99.0% (TLC)

Synonym(s):

5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O2
CAS Number:
5355-16-8
Molecular Weight:
260.29
Beilstein:
258464
EC Number:
226-333-3
MDL number:
MFCD00057349
UNSPSC Code:
41116107
PubChem Substance ID:
329798904
NACRES:
NA.24

grade

analytical standard

Quality Level

200

Assay

≥99.0% (TLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(Cc2cnc(N)nc2N)cc1OC

InChI

1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)

InChI key

LDBTVAXGKYIFHO-UHFFFAOYSA-N

Gene Information

rat ... Dhfr(24312)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000352711
0000354711
0000284086
0000337289
0000352711

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Sigma-Aldrich

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Residue Reviews: Residues of Pesticides and Other Contaminants in the Total Environment (2012)
P Tömpe et al.
Acta pharmaceutica Hungarica, 60(1), 23-29 (1990-01-01)
Differential pulse polarographic method was applied for determination of diaveridine in plasma, whole blood and isolated organs (liver, spleen, kidney, thymus). Deproteinization of homogenized blood and organs had been carried out on Extrelut column and then concentration of diaveridine was
A Tanabe et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 86(6), 411-415 (1985-12-01)
The preventive effect of sulfaquinoxaline and diaveridine in combination against leucocytozoon infection in White Leghorn female chickens was tested in a field trial. The experiment was initiated when the animals were 120 days old, and it lasted for 10 weeks.
Determination of residual diaveridine and sulfaquinoxaline in Hen's egg, chicken plasma and tissues by high-performance liquid chromatography.
T Sakano et al.
Chemical & pharmaceutical bulletin, 29(8), 2290-2295 (1981-08-01)
Tomoko Ono-Ogata et al.
Environmental and molecular mutagenesis, 39(1), 43-48 (2002-01-29)
We examined the mutagenic activities of six antiprotozoal drugs (three diaminopyrimidine compounds [pyrimethamine, diaveridine, and trimethoprim] and three 8-aminoquinoline derivatives [primaquine, pentaquine, and pamaquine]) in Escherichia coli WP2uvrA/pKM101 and Salmonella typhimurium TA100 and TA98 with and without nitrite treatment. The
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