34039

Marbofloxacin

VETRANAL^®, analytical standard

• Synonym(s): 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid, Zeniquin^®
• Empirical Formula (Hill Notation): C₁₇H₁₉FN₄O₄
• CAS Number: 115550-35-1
• Molecular Weight: 362.36
• MDL number: MFCD00864820
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754775
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O
• InChI: 1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
• InChI key: BPFYOAJNDMUVBL-UHFFFAOYSA-N

Description

General description

Marbofloxacin belongs to the group of synthetic fluoroquinolone compounds, widely used as a veterinary anti-bacterial drug. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria.

Application

The analytical standard can be used as follows:

• Surface-enhanced Raman spectroscopy-based determination of marbofloxacin in chicken and duck samples using β-cyclodextrin-modified silver nanoparticles (β-CD-AgNPs)
• Analysis of synovial fluid and plasma samples obtained from dairy cows for marbofloxacin by high-performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS/MS) following ultrafiltration of the samples
• Development of an indirect competitive ELISA (icELISA) method for the combined analysis of marbofloxacin and ofloxacin in raw milk and porcine samples
• Multi-residue analysis of oxolinic acid, flumequine, marbofloxacin, and enrofloxacin in commercial honey samples by micellar liquid chromatography coupled with fluorescence detection
• Simultaneous determination of marbofloxacin and trovafloxacin in sheep plasma samples by HPLC combined with UV detection
• Quantification of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Zeniquin is a registered trademark of Pfizer, Inc.

Safety Information

• Hazard Statements: H412
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves