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Clothianidin

PESTANAL®, analytical standard

Synonym(s):

(E)-1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine

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About This Item

Empirical Formula (Hill Notation):
C6H8ClN5O2S
CAS Number:
Molecular Weight:
249.68
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

CN\C(NCc1cnc(Cl)s1)=N/[N+]([O-])=O

InChI

1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)

InChI key

PGOOBECODWQEAB-UHFFFAOYSA-N

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General description

Clothianidin is a neonicotinoid insecticide with excellent systemic action for a wide variety of insect pests, that acts effectively on nicotinic acetylcholine receptors (nAChR).
Find more information here: Neonicotinoids

Application

Clothianidin may be used as a reference standard for the analysis of the analyte in agricultural samples using dual-labeled time-resolved fluoro-immunoassay (TRFIA), followed by gas chromatography (GC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pricing

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Chemistry of clothianidin and related compounds.
Uneme H.
Journal of Agricultural and Food Chemistry, 59(7), 2932-2937 (2010)
Gennaro Di Prisco et al.
Scientific reports, 7(1), 13446-13446 (2017-10-19)
Clothianidin is a widely used neonicotinoid insecticide, which is a potent agonist of the nicotinic acetylcholine receptor in insects. This neurotoxic compound has a negative impact on insect immunity, as it down-regulates the activation of the transcription factor NF-κB. Given
Christof W Schneider et al.
PloS one, 7(1), e30023-e30023 (2012-01-19)
The development of insecticides requires valid risk assessment procedures to avoid causing harm to beneficial insects and especially to pollinators such as the honeybee Apis mellifera. In addition to testing according to current guidelines designed to detect bee mortality, tests
Thiamethoxam is a neonicotinoid precursor converted to clothianidin in insects and plants.
Nauen R, et al.
Pesticide Biochemistry and Physiology, 76(2), 55-69 (2003)
Antoine Abrieux et al.
PloS one, 11(11), e0167469-e0167469 (2016-12-03)
Neonicotinoid insecticides are widely used to protect plants against pest insects, and insecticide residues remaining in the environment affect both target and non-target organisms. Whereas low doses of neonicotinoids have been shown to disturb the behaviour of pollinating insects, recent

Protocols

Learn more about Neonicotinoids - active substances used in plant protection products to control harmful insects.

Learn more about Neonicotinoids - active substances used in plant protection products to control harmful insects.

Learn more about Neonicotinoids - active substances used in plant protection products to control harmful insects.

Learn more about Neonicotinoids - active substances used in plant protection products to control harmful insects.

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