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30050

Sigma-Aldrich

Cystamine dihydrochloride

purum, ≥98.0% (AT)

Synonym(s):

2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride

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About This Item

Linear Formula:
NH2CH2CH2SSCH2CH2NH2 · 2HCl
CAS Number:
56-17-7
Molecular Weight:
225.20
Beilstein:
3616850
EC Number:
200-260-7
MDL number:
MFCD00012905
UNSPSC Code:
12352100
PubChem Substance ID:
329753417
NACRES:
NA.22

grade

purum

Quality Level

200

Assay

≥98.0% (AT)

form

powder

mp

217-220 °C (dec.) (lit.)
~220 °C (dec.)

solubility

water: soluble 1 g/10 mL, clear, colorless

functional group

amine
disulfide

SMILES string

Cl[H].Cl[H].NCCSSCCN

InChI

1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key

YUFRRMZSSPQMOS-UHFFFAOYSA-N

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Application

Cystamine dihydrochloride was used:
  • as sulfhydryl modifying reagent
  • in synthesis of monoclonal anti-prostate-specific membrane antigen antibody and A9 RNA aptamers-conjugated popcorn shape gold nanoparticles
  • as internal standard in determination of total homocysteine
  • in modification of gold nanorod surface by amine groups

Other Notes

Sulfhydryl modifying reagent

related product

Product No.
Description
Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM1446
BCCK0619
BCBV7893
BCBS3508V
BCBT1874

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Anant K Singh et al.
ACS nano, 3(7), 1906-1912 (2009-07-04)
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Wentong Lu et al.
Journal of the American Chemical Society, 132(51), 18103-18114 (2010-12-07)
Prostate cancer is the second leading cause of cancer-related death among the American male population, and the cost of treating prostate cancer patients is about $10 billion/year in the United States. Current treatments are mostly ineffective against advanced-stage prostate cancer
L J Riddell et al.
The American journal of clinical nutrition, 71(6), 1448-1454 (2000-06-06)
Elevated plasma total homocysteine (tHcy) concentrations are associated with increased risk of vascular disease, and there is a strong inverse association between dietary and blood folate and blood tHcy concentrations. Increased folate consumption may lower the risk of tHcy-mediated cardiovascular
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International journal of nanomedicine, 14, 4833-4847 (2019-07-17)
The use of functionalized graphene oxide (fGO) has led to a new trend in the sensor field, owing to its high sensitivity with regards to sensing characteristics and easy synthesis procedures. In this study, we developed an ultra-sensitive carboxyl-graphene oxide
J E Bodwell et al.
Biochemistry, 23(7), 1392-1398 (1984-03-27)
Glucocorticoid -receptor complexes from intact rat thymus cells incubated with [3H]dexamethasone at 0 degree C are in the nonactivated form and do not bind to DNA-cellulose. Upon being warmed, they are transformed to activated complexes that bind to DNA-cellulose at
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