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01310

Sigma-Aldrich

N-Acetyl-L-methionine

≥98.5% (T)

Synonym(s):

N-acetyl-L-lysine

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About This Item

Linear Formula:
CH3SCH2CH2CH(NHCOCH3)CO2H
CAS Number:
65-82-7
Molecular Weight:
191.25
Beilstein:
1725552
EC Number:
200-617-7
MDL number:
MFCD00064441
UNSPSC Code:
12352209
PubChem Substance ID:
329747249
NACRES:
NA.22

Quality Level

100

Assay

≥98.5% (T)
≥98.5% (TLC)

form

powder or crystals

optical activity

[α]20/D -21.0±1.0°, c = 1% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

103-106 °C (lit.)

solubility

methanol: 50 mg/mL, clear to very slightly hazy, colorless

application(s)

peptide synthesis

SMILES string

CSCC[C@H](NC(C)=O)C(O)=O

InChI

1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1

InChI key

XUYPXLNMDZIRQH-LURJTMIESA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7455
BCCJ4944
BCCF0218
BCCC4556
BCBW4457

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Agnieszka Kołodziejczak-Radzimska et al.
Biotechnology progress, 34(3), 767-777 (2018-01-10)
Acylase I from Aspergillus melleus was immobilized on supports consisting of unmodified and modified silica. Modification was performed using 3-aminopropyltriethoxysilane (APTES) and glutaraldehyde (GA). The effectiveness of immobilization was investigated using the standard Bradford method in addition to a number
Mie R Rasmussen et al.
Journal of proteome research, 15(12), 4591-4600 (2016-11-05)
Loss-of-function mutations in the transmembrane ABCC6 transport protein cause pseudoxanthoma elasticum (PXE), an ectopic, metabolic mineralization disorder that affects the skin, eye, and vessels. ABCC6 is assumed to mediate efflux of one or several small molecule compounds from the liver
Christian Schöneich et al.
Journal of the American Chemical Society, 125(45), 13700-13713 (2003-11-06)
The pathogenesis of Alzheimer's disease is strongly associated with the formation and deposition of beta-amyloid peptide (beta AP) in the brain. This peptide contains a methionine (Met) residue in the C-terminal domain, which is important for its neurotoxicity and its
M Mályusz et al.
Renal physiology and biochemistry, 17(6), 307-315 (1994-11-01)
Hippurate is known to be synthesized from benzoate and glycine in the liver and kidney. It takes part in renal ammoniagenesis by modulating the activity of gamma-glutamyl transpeptidase (gamma GT). Due to its chemical structure, however, hippurate might also serve
Rebecca D Sandlin et al.
Journal of inorganic biochemistry, 104(2), 214-216 (2009-11-13)
A bulky platinum triamine complex, [Pt(Me(5)dien)(NO(3))]NO(3) (Me(5)dien=N,N,N',N',N''-pentamethyldiethylenetriamine) has been prepared and reacted in D(2)O with N-acetylmethionine (N-AcMet) and guanosine 5'-monophosphate (5'-GMP); the reactions have been studied using (1)H NMR spectroscopy. Reaction with 5'-GMP leads to two rotamers of [Pt(Me(5)dien)(5'-GMP-N7)](+). Reaction
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