ELISA: suitable immunofluorescence: suitable immunohistochemistry: suitable (paraffin) western blot: suitable
shipped in
wet ice
Specificity
Specific to HCV NS3, helicase domain.
Immunogen
Recombinant protein to NS3
Application
Anti-Hepatitis C Virus Antibody, helicase domain NS3 detects level of Hepatitis C Virus & has been published & validated for use in ELISA, IF, WB, IH(P).
ELISA
Immunohistochemistry (Parrafin embedded)
Immunofluorescence
Immunoblot
Final dilutions must be determined by end user
Research Category Infectious Diseases
Research Sub Category Infectious Diseases - Viral
Physical form
Format: Purified
Liquid in PBS, pH 7.4 containing no preservatives
Storage and Stability
Store at -20°C in undiluted aliquots for up to 6 months from date of receipt; avoid repeated freeze-thaw cycles; short-term storage (1 week) can be at 2-8°C. Use with sterile tips to prevent contamination.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Molecular medicine reports, 12(4), 5109-5115 (2015-07-08)
Chronic hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) worldwide. The HCV non‑structural protein 3 (NS3) protein is considered to affect normal cellular functions and to be involved in HCV carcinogenesis. The expression of microRNA
The Kobe journal of medical sciences, 69(3), E86-E95 (2023-09-04)
We previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. Activation of JNK contributes to the development of liver diseases, including metabolic disorders, steatosis, liver cirrhosis and hepatocellular carcinoma. JNK
The Kobe journal of medical sciences, 67(2), E38-E47 (2021-11-20)
We previously reported that hepatitis C virus (HCV) NS5A (1b, Con1) protein accepts covalent ISG15 conjugation at specific lysine (Lys) residues (K44, K68, K166, K215 and K308), exhibiting proviral effects on HCV RNA replication. Here we investigated a role of
Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone
A large amount of epidemiological evidence indicates that persistent HCV infection is the main risk factor for HCC. We aimed to study the effects of persistent HCV infection on the interaction of the virus and host cell to identify cancer
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.