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AB9348

Sigma-Aldrich

Anti-Myelin Basic Protein Antibody

CHEMICON®, chicken polyclonal

Synonym(s):

Anti-C76307, Anti-Hmbpr, Anti-R75289, Anti-golli-mbp, Anti-jve, Anti-mld, Anti-shi

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

product name

Anti-Myelin Basic Protein Antibody, Chemicon®, from chicken

biological source

chicken

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

NCBI accession no.

NM_001025081.1
NM_001025090.1
NM_001025092.1
NM_001025094.1
NM_001025098.1
NM_001025100.1
NM_001025101.1
NM_002385.2

UniProt accession no.

P02686

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MBP(4155)
mouse ... Mbp(17196)

Specificity

Recognizes Myelin Basic Protein (MBP).

Immunogen

Synthetic peptide from human/mouse MBP.

Application

Anti-Myelin Basic Protein Antibody detects level of Myelin Basic Protein & has been published & validated for use in IC, IH.
Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues.

Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins

Physical form

Affinity purified chicken IgY. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that you store the antibody in the dark.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description
Pricing

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Caroline Guglielmetti et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(33), E6982-E6991 (2017-08-02)
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C Guglielmetti et al.
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Although MRI is the gold standard for the diagnosis and monitoring of multiple sclerosis (MS), current conventional MRI techniques often fail to detect cortical alterations and provide little information about gliosis, axonal damage and myelin status of lesioned areas. Diffusion
The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.
Einheber, S; Meng, X; Rubin, M; Lam, I; Mohandas, N; An, X; Shrager, P; Kissil, J; Maurel et al.
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Elodie Martin et al.
Brain plasticity (Amsterdam, Netherlands), 5(2), 123-133 (2020-12-08)
Microglia are the resident macrophages of the central nervous system (CNS). In multiple sclerosis (MS) and related experimental models, microglia have either a pro-inflammatory or a pro-regenerative/pro-remyelinating function. Inhibition of Bruton's tyrosine kinase (BTK), a member of the Tec family
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