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Key Documents

AB9016

Sigma-Aldrich

Anti-Chx10 Antibody, NT

Chemicon®, from sheep

Synonym(s):

Hox-10, Ocular Retardation, C. Elegans ceh-10 Homeo Domain Containing Homolog

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

sheep

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

bovine, human, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... VSX2(338917)

Specificity

Chx10

Immunogen

Epitope: N-terminus
Recombinant human Chx10 protein, N-terminal.

Application

Detect Chx10 using this Anti-Chx10 Antibody, N-terminus validated for use in WB.
Immunoblotting: 0.5-1.0 μg/mL. Reacts with the 46 kD protein in rat and mouse retinal tissue lysate.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bikun Xian et al.
Stem cells international, 2019, 7148032-7148032 (2019-08-21)
We investigated the efficacy of the immunosuppressants rapamycin (RAP) and dexamethasone (DEX) in improving the survival of retinal organoids after epiretinal transplantation. We first compared the immunosuppressive abilities of DEX and RAP in activated microglia in an in vitro setting.
D Leonardo Garcia-Ramirez et al.
Frontiers in neural circuits, 16, 957084-957084 (2022-08-23)
Spinal cord neurons integrate sensory and descending information to produce motor output. The expression of transcription factors has been used to dissect out the neuronal components of circuits underlying behaviors. However, most of the canonical populations of interneurons are heterogeneous
Mary P Moore et al.
American journal of physiology. Gastrointestinal and liver physiology, 320(4), G564-G572 (2021-01-28)
Nutritional ketosis as a therapeutic tool has been extended to the treatment of metabolic diseases, including obesity, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD). The purpose of this study was to determine whether dietary administration of the ketone
Sangbae Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(22), 10824-10833 (2019-05-11)
Rod and cone photoreceptors are light-sensing cells in the human retina. Rods are dominant in the peripheral retina, whereas cones are enriched in the macula, which is responsible for central vision and visual acuity. Macular degenerations affect vision the most
Ziming Luo et al.
Stem cells (Dayton, Ohio), 36(11), 1709-1722 (2018-07-13)
Effective derivation of three-dimensional (3D) retinal tissue from human-induced pluripotent stem cells (hiPSCs) could provide models for drug screening and facilitate patient-specific retinal cell replacement therapy. However, some hiPSC lines cannot undergo 3D self-organization and show inadequate differentiation efficiency to

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