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Key Documents

AB1857

Sigma-Aldrich

Anti-Osteocalcin Antibody, a.a. 1-22

serum, Chemicon®

Synonym(s):

Anti-BGP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
radioimmunoassay: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BGLAP(632)

Specificity

Recognizes human osteocalcin (1-22) mature form. Also reacts with osteocalcin (1-44) and osteocalcin (1-49). No reactivity with human bone sialoprotein and human osteonectin.

Immunogen

Epitope: a.a. 1-22
Synthetic peptide corresponding to amino acids 1-22 of human Osteocalcin (MRALTLLALLALAALCIAGQAG).

Application

Anti-Osteocalcin Antibody, a.a. 1-22 detects level of Osteocalcin & has been published & validated for use in ELISA, RIA.
RIA (1:2000)

ELISA (1:5000)

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors

Linkage

Replaces: MABD182

Physical form

Rabbit serum. Lyophilized. Reconstitute with 100 μL of sterile distillled water.

Storage and Stability

Maintain lyophilized material at 2-8°C. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Laurent A Tchang et al.
Journal of tissue engineering and regenerative medicine, 11(5), 1542-1552 (2015-06-17)
The use of fetal bovine serum (FBS) as a culture medium supplement in cell therapy and clinical tissue engineering is challenged by immunological concerns and the risk of disease transmission. Here we tested whether human, thrombin-activated, pooled, platelet-rich plasma (tPRP)
Huawen Ding et al.
Journal of cell science, 125(Pt 22), 5564-5577 (2012-09-05)
Nitric oxide (NO) has been shown to play a crucial role in bone formation in vivo. We sought to determine the temporal effect of NO on murine embryonic stem cells (ESCs) under culture conditions that promote osteogenesis. Expression profiles of
Rodrigo A Grandy et al.
Molecular and cellular biology, 36(4), 615-627 (2015-12-09)
Stem cell phenotypes are reflected by posttranslational histone modifications, and this chromatin-related memory must be mitotically inherited to maintain cell identity through proliferative expansion. In human embryonic stem cells (hESCs), bivalent genes with both activating (H3K4me3) and repressive (H3K27me3) histone
Laminin-5 induces osteogenic gene expression in human mesenchymal stem cells through an ERK-dependent pathway.
Klees, RF; Salasznyk, RM; Kingsley, K; Williams, WA; Boskey, A; Plopper, GE
Molecular Biology of the Cell null
Elena Filová et al.
International journal of nanomedicine, 9, 3687-3706 (2014-08-16)
Hydroxyapatite (HA) is considered to be a bioactive material that favorably influences the adhesion, growth, and osteogenic differentiation of osteoblasts. To optimize the cell response on the hydroxyapatite composite, it is desirable to assess the optimum concentration and also the

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