288500-M
DL-α-Difluoromethylornithine, Hydrochloride
A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis.
Synonym(s):
DL-α-Difluoromethylornithine, Hydrochloride, DFMO, Eflornithine, RMI-71782
About This Item
Recommended Products
Quality Level
Assay
≥99% (TLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL
methanol: 25 mg/mL
storage temp.
10-30°C
InChI
1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
InChI key
FJPAMFNRCFEGSD-UHFFFAOYSA-N
1 of 4
This Item | 29081-U | 29109-U | 29122-U |
---|---|---|---|
closure type screw top vial | closure type screw top vial | closure type screw top vial | closure type screw top vial |
thread for 9 mm | thread for 9 mm | thread for 8-425 | thread for 10-425 |
amber glass vial | clear glass vial | clear glass vial | clear glass vial |
Interlocked vial (with fused-in insert) | Interlocked vial (with fused-in insert) | Interlocked vial (with fused-in insert) | Interlocked vial (with fused-in insert) |
pkg of 100 ea | pkg of 100 ea | pkg of 100 ea | pkg of 100 ea |
General description
Biochem/physiol Actions
ODC
Warning
Reconstitution
Other Notes
Feuerstein, B.G., et al. 1992. Cancer Res. 52, 6782.
Takigawa, M., et al. 1990. Cancer Res.50, 4131.
Weeks, C.E., et al. 1982. Proc. Natl. Acad. Sci. USA 79, 6028.
Danzin, C., et al. 1979. Life Sci. 24, 519.
Legal Information
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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