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Key Documents

12-243

Sigma-Aldrich

S6 Kinase/Rsk2 Substrate Peptide 2

S6 Kinase/Rsk2 Substrate Peptide 2 primarily used in Kinase Assays.

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

Quality Level

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

human ... RPS6KA3(6197)

Biochem/physiol Actions

Protein Target: Rsk2
Target Sub-Family: AGC

Quality

Routinely evaluated as a substrate for p90 Rsk-2 and p70 S6 Kinase.

Physical form

Lyophilized powder

Storage and Stability

Lyophilized: Stable for 2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytes
Tirosh, A., et al
The Biochemical Journal, 355, 757-763 (2001)
C J Band et al.
The Journal of biological chemistry, 272(1), 138-145 (1997-01-03)
The hormonal regulation of insulin-like growth factor binding protein (IGFBP)-1 and -4 mRNA was compared in serum-free primary rat hepatocyte cultures. The combination of dexamethasone and glucagon (Dex/Gluc) strongly increased IGFBP-1 and IGFBP-4 mRNA levels. Insulin suppressed Dex/Gluc-stimulated IGFBP-1 but

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