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O-002

Supelco

Oxycodone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H21NO4
CAS Number:
Molecular Weight:
315.36
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

InChI key

BRUQQQPBMZOVGD-XFKAJCMBSA-N

Gene Information

human ... OPRM1(4988)

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General description

This Certified Spiking Solution® is suitable for numerous applications in GC/MS or LC/MS testing of oxycodone from clinical toxicology and urine drug testing to forensic analysis. Oxycodone is a semi-synthetic opioid analgesic sold under many trade names including OxyContin® and Percocet® for treatment of moderate to severe pain. Oxycodone is also sold illicitly under street names such as "Roxies," "Blues," and "Perks".

Application


  • OxycoDonesolution in pediatric perioperative care: OxycoDonesolution has been investigated for its compatibility with other perioperative medications in pediatric settings using Y-type connectors, contributing to safe and effective pain management protocols in children (Youssef et al., 2024).

  • Analytical testing of oxycodone: OxycoDonesolution is utilized in advanced analytical techniques, such as substrate spray mass spectrometry, for the detection of oxycoDoneand naloxone in saliva, showcasing its application in rapid and sensitive diagnostic settings (Millán-Santiago et al., 2024).

  • Study on opioid receptor agonist in exercise physiology: Research has explored the interaction of opioid receptor agonists, including oxycodone, with other compounds in modulating physiological responses to exercise, indicating its role in complex physiological studies (Anselmi et al., 2024).

  • Pharmacological evaluation for pain management: OxycoDonesolution is employed in multivalent vaccination strategies against opioid exposure, providing insights into the development of therapeutic interventions aimed at opioid-related disorders (Song et al., 2024).

  • Quantitative analysis of analgesics: Utilizing HPLC-DAD and LC-MS/MS methods, oxycoDonesolution is critical in the simultaneous determination of multiple analgesics in postoperative solutions, highlighting its importance in pharmacokinetic research and drug monitoring (Yao et al., 2024).

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Prescrire international, 22(134), 10-11 (2013-02-02)
At high doses of oxycodone, the fixed-dose combination of oxycodone plus naloxone complicates therapeutic management and will likely have lower analgesic efficacy.
Reply to commentary.
Stephen F Butler
The journal of pain : official journal of the American Pain Society, 14(4), 361-362 (2013-04-04)
Raymond E Glazier et al.
Disability and health journal, 6(2), 107-115 (2013-03-20)
Substance abuse (SA) is a grave and pervasive social problem associated with severe personal and social costs that affect persons with disabilities disproportionally. Most previous research has found SA prevalence to be greater among persons with disabilities than among those
Dustin B Stephens et al.
Journal of studies on alcohol and drugs, 74(3), 386-395 (2013-03-16)
Alcohol consumption dramatically increases the risk of liver damage among those with hepatitis C virus (HCV) infection, yet the impact of HCV status disclosure and standard informational counseling on alcohol use among rural drug users remains poorly understood. In this
James P Zacny et al.
Experimental and clinical psychopharmacology, 21(2), 103-111 (2013-02-21)
Two prominent and important risk factors for nonmedical use of prescription opioids (NMUPO) identified in epidemiological studies are smoking status and sex (i.e., there is a greater likelihood of NMUPO in smokers and in men, relative to nonsmokers and women).

Articles

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

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