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Key Documents

T24503

Sigma-Aldrich

Tetramethylurea

99%

Synonym(s):

1,1,3,3-Tetramethylurea, TMU

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About This Item

Linear Formula:
(CH3)2NCON(CH3)2
CAS Number:
Molecular Weight:
116.16
Beilstein:
773898
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

refractive index

n20/D 1.451 (lit.)

bp

177 °C (lit.)
62-63 °C/12 mmHg (lit.)

mp

−1 °C (lit.)

density

0.968 g/mL at 20 °C (lit.)

SMILES string

CN(C)C(=O)N(C)C

InChI

1S/C5H12N2O/c1-6(2)5(8)7(3)4/h1-4H3

InChI key

AVQQQNCBBIEMEU-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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Application

  • Role of Tetramethylurea in Synthesizing Mesoporous Alumina: Tetramethylurea was used to synthesize mesoporous alumina via a hydrothermal method, affecting pore structure and thermal stability (Ghosh et al., 2014).

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

167.0 °F - closed cup

Flash Point(C)

75 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yoshikata Koga et al.
The journal of physical chemistry. B, 115(12), 2995-3002 (2011-03-10)
We have developed what we call the 1-propanol(1P) probing methodology. By using it, we determined the relative hydrophobicity/hydrophilicity indices of 2-butoxyethanol, a typical hydrophobe; urea, a typical hydrophile; and trimethylamine-N-oxide, an amphiphile. By comparing these indices with those for other
Haiyan Wei et al.
The journal of physical chemistry. B, 114(1), 557-568 (2009-11-26)
The effects of urea, tetramethyl urea (TMU), and trimethylamine N-oxide (TMAO) on the structure and dynamics of aqueous solutions are studied using molecular dynamics simulations. It was found that urea has little effects on the water-water hydrogen-bond length and angle
V Labrie et al.
Biochimica et biophysica acta, 1535(2), 128-133 (2001-05-09)
Using a chemical cross-linker and gel electrophoresis or a dot blot overlay assay, we studied protein-protein interaction of STb toxin, a 48-residue amphiphilic polypeptide causing intestinal disorders. For the first time, we report on the oligomerization property of STb. This
Marcelo A da Silva et al.
Journal of colloid and interface science, 289(2), 394-401 (2005-06-07)
In this work, the gelation kinetics and fractal character of lysozyme gel matrices developed in tetramethylurea (TMU)-water media were investigated. Gelation times were determined from the temporal crossover point between the storage, G', and loss, G'', moduli, as a function
Kamila Mazur et al.
The journal of physical chemistry. B, 115(11), 2563-2573 (2011-03-02)
The nature and extent of the effects that hydrophilic and hydrophobic solutes have on the dynamics of water molecules continues to be an area of intense experimental and theoretical investigation. In this work, we use the ultrafast optical Kerr effect

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