QBD10931

m-dPEG^®₃₆-MAL

>95% (HPLC)

• Synonym(s): mPEG₃₆-MAL, mPEG-maleimide, mPEG₁₅₀₀-maleimide, mPEG₃₆-maleimide
• Empirical Formula (Hill Notation): C₈₀H₁₅₄N₂O₃₉
• Molecular Weight: 1768.07
• MDL number: MFCD21363231
• UNSPSC Code: 12352200
• NACRES: NA.22

Properties

• Assay: >95% (HPLC)
• form: solid or viscous liquid
• reaction suitability: reaction type: Pegylations
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C

Description

Features and Benefits

m-dPEG₃₆-MAL is a methyl-terminated, thiol-reactive, monodispersed PEGylation product designed for surface and biomolecule modification. This single molecular weight PEG reagent has a discrete chain length of 116 atoms spanning a distance of 132.4 Å. One end of the molecule terminates in a maleimido-propionic acid group, which is conjugated to the dPEG spacer by an amide bond. The maleimide moiety reacts with sulfhydryls to form a thioether bond. dPEG₃₆ is a monodisperse equivalent of the polymeric PEG₁₅₀₀. Modification of cysteine residues on peptides, proteins, and other sulfhydryl-containing molecules with m-dPEG₃₆-MAL will increase hydrophilicity and decrease immunogenicity.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable