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Key Documents

G11608

Sigma-Aldrich

Guanidineacetic acid

99%

Synonym(s):

N-Amidinoglycine, N-Guanylglycine, Glycocyamine

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About This Item

Linear Formula:
H2NC(=NH)NHCH2CO2H
CAS Number:
Molecular Weight:
117.11
Beilstein:
1759179
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

mp

300 °C (lit.)

SMILES string

NC(=N)NCC(O)=O

InChI

1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)

InChI key

BPMFZUMJYQTVII-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Carla Valongo et al.
Clinica chimica acta; international journal of clinical chemistry, 348(1-2), 155-161 (2004-09-17)
A new gas chromatography-mass spectrometry method for routine quantification of urine creatine and guanidinoacetic acid (GAA) has been developed to provide a fast, reliable and inexpensive metabolic screening. Our method uses a two-step derivatization procedure which involves a reaction with
Rafael Deminice et al.
The Journal of nutrition, 141(10), 1799-1804 (2011-09-02)
The aim of the present study was to examine the effects of creatine supplementation on liver fat accumulation induced by a high-fat diet in rats. Rats were fed 1 of 3 different diets for 3 wk: a control liquid diet
J Michiels et al.
Poultry science, 91(2), 402-412 (2012-01-19)
Creatine, (CREA) a central constituent in energy metabolism, is obtained from dietary animal protein or de novo synthesis from guanidinoacetic acid (GAA). Especially in all-vegetable diets, supplemental CREA or GAA may restore the CREA availability in tissues, and hence, improve
Saadet Mercimek-Mahmutoglu et al.
Molecular genetics and metabolism, 105(1), 155-158 (2011-10-25)
A 4-year-old female with history of developmental regression and autistic features was diagnosed with guanidinoacetate methyltransferase deficiency at age 21 months. Upon treatment, she showed improvements in her developmental milestones, sensorial-neural hearing loss and brain atrophy on cranial-MRI. The creatine/choline
S Stöckler et al.
Pediatric research, 36(3), 409-413 (1994-09-01)
In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis

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