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Key Documents

D115606

Sigma-Aldrich

1,5-Dihydroxynaphthalene

97%

Synonym(s):

1,5-Naphthalenediol

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About This Item

Linear Formula:
C10H6(OH)2
CAS Number:
Molecular Weight:
160.17
Beilstein:
2044951
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

259-261 °C (dec.) (lit.)

SMILES string

Oc1cccc2c(O)cccc12

InChI

1S/C10H8O2/c11-9-5-1-3-7-8(9)4-2-6-10(7)12/h1-6,11-12H

InChI key

BOKGTLAJQHTOKE-UHFFFAOYSA-N

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Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T J Holmes et al.
Biochemical and biophysical research communications, 123(1), 156-162 (1984-08-30)
Irreversible inhibition of soybean lipoxygenase-1 (SL-1) was accomplished via a controlled potential oxidative electrolysis of 1,5-dihydroxynaphthalene (1,5-DHN) at +0.8 V vs SCE. The inactivation of SL-1 with this known inhibitor was greatly enhanced under these electrolytic conditions to which the
J Baumann et al.
Prostaglandins, 20(4), 627-639 (1980-10-01)
Until now only few data have been reported on biochemically explicable pharmacological effects of flavonoid structures. When tested against arachidonic acid metabolism many flavonoids were found to be effective against the lipoxygenase and cyclo-oxygenase pathways. Some flavonoids were predominant inhibitors
S Gal et al.
Chemistry and physics of lipids, 150(2), 186-203 (2007-09-29)
Copper-induced peroxidation of liposomal palmitoyllinoleoyl-phosphatidylcholine (PLPC) is inhibited by alpha-tocopherol at micromolar concentrations. In our previous study we found that when the liposomes contain phosphatidylserine (PS), nanomolar concentrations of Toc were sufficient to inhibit peroxidation. In an attempt to gain
Shin-ya Takizawa et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 10(6), 895-903 (2011-02-08)
Photooxidation reactions of 1,5-dihydroxynaphthalene (DHN) have been carried out in the presence of cyclometalated neutral and cationic iridium (Ir) complexes 1-6 as singlet oxygen ((1)O(2)) sensitizers in order to investigate the (1)O(2) generation quantum yield and photosensitizing durability of the
Interactions of sulfhydryl agents and soybean lipoxygenase inhibitors.
I Knippel et al.
Biochemical pharmacology, 30(12), 1677-1684 (1981-06-15)

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