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A55500

Sigma-Aldrich

2-Aminofluorene

98%

Synonym(s):

2-Fluorenamine, 2-Fluorenylamine

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About This Item

Empirical Formula (Hill Notation):
C13H11N
CAS Number:
153-78-6
Molecular Weight:
181.23
Beilstein:
1945861
EC Number:
205-817-8
MDL number:
MFCD00001125
UNSPSC Code:
12352100
PubChem Substance ID:
24890992
NACRES:
NA.22

Quality Level

100

Assay

98%

form

powder

mp

124-128 °C (lit.)

SMILES string

Nc1ccc-2c(Cc3ccccc-23)c1

InChI

1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2

InChI key

CFRFHWQYWJMEJN-UHFFFAOYSA-N

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Related Categories

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H351,H411

Hazard Classifications

Aquatic Chronic 2 - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

299758

2-Nitro-9-fluorenone

Nidhi Jain et al.
Chemical research in toxicology, 21(2), 445-452 (2008-01-16)
Fluorescence spectroscopy was used to study carcinogen-induced conformational heterogeneity in DNA duplexes. The fluorophore 2-aminopurine (AP) was incorporated adjacent (5') to the lesion (G*) in eight different DNA duplexes [d(5'-CTTCT PG* NCCTC-3'):d(5'-GAGGN XTAGAAG-3'), G* = FAF adduct, P = AP
Olga Rechkoblit et al.
Nature structural & molecular biology, 17(3), 379-388 (2010-02-16)
The aromatic amine carcinogen 2-aminofluorene (AF) forms covalent adducts with DNA, predominantly with guanine at the C8 position. Such lesions are bypassed by Y-family polymerases such as Dpo4 via error-free and error-prone mechanisms. We show that Dpo4 catalyzes elongation from
Jun Zhao et al.
Stem cell research & therapy, 10(1), 165-165 (2019-06-15)
Mounting evidence has shown that a novel subset of mesenchymal stem cells (MSCs) derived from human gingiva referred to as gingival mesenchymal stem cells (GMSCs) displays a greater immunotherapeutic potential and regenerative repair expression than MSCs obtained from other tissues.
Ali Bilici et al.
Biomacromolecules, 11(10), 2593-2601 (2010-09-08)
In this paper, the results on horseradish peroxidase (HRP)-catalyzed oxidative polymerization of amine-functionalized fluorene monomer, 2-amino fluorene (AF), are reported. The resulting polymer exhibits an exciting molecular structure and spectral properties. FT-IR and NMR studies show that the two fluorene
R H Heflich et al.
Mutation research, 318(2), 73-114 (1994-10-01)
2-Acetylaminofluorene and 2-aminofluorene are among the most intensively studied of all chemical mutagens and carcinogens. Fundamental research findings concerning the metabolism of 2-acetylaminofluorene to electrophilic derivatives, the interaction of these derivatives with DNA, and the carcinogenic and mutagenic responses that
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