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A54059

Sigma-Aldrich

2-(2-Aminoethoxy)ethanol

98%

Synonym(s):

Diethylene glycolamine

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About This Item

Linear Formula:
NH2CH2CH2OCH2CH2OH
CAS Number:
929-06-6
Molecular Weight:
105.14
Beilstein:
906728
EC Number:
213-195-4
MDL number:
MFCD00008181
UNSPSC Code:
12352100
PubChem Substance ID:
24890972
NACRES:
NA.22

Quality Level

200

Assay

98%

form

liquid

bp

218-224 °C (lit.)

density

1.048 g/mL at 25 °C (lit.)

SMILES string

NCCOCCO

InChI

1S/C4H11NO2/c5-1-3-7-4-2-6/h6H,1-5H2

InChI key

GIAFURWZWWWBQT-UHFFFAOYSA-N

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Application

2-(2-Aminoethoxy)ethanol is commonly used as a spacer/linker in the synthesis of bioconjugate materials for applications such as drug delivery and protein labeling. It is also employed as a receptor chain in the preparation of carboxamidoquinoline based water-soluble, ratiometric fluorescent zinc sensor.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

260.6 °F

Flash Point(C)

127 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores.
Lee, Hsiao-lu D et al.
Journal of the American Chemical Society, 132(43), 15099-15101 (2010)
C Tournaire-Arellano et al.
Carbohydrate research, 314(1-2), 47-63 (1999-05-07)
Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and were evaluated on Trichomonas vaginalis NAHase. Although none showed complete inhibition of the enzyme at 100 microM, 1-amino-1-deoxy-D-glucitol derivatives acted as competitive inhibitors of
Ratiometric and water-soluble fluorescent zinc sensor of carboxamidoquinoline with an alkoxyethylamino chain as receptor.
Zhang, Yu et al.
Organic Letters, 10(3), 473-476 (2008)
Cao-An Vu et al.
ACS omega, 4(12), 14765-14771 (2019-09-26)
Silicon nanowire field-effect transistors (SiNW-FETs) have been demonstrated as a highly sensitive platform for label-free detection of a variety of biological and chemical entities. However, detecting signal from immunoassays by nano-FETs is severely hindered by the distribution of different charged
Xiuxuan Zhang et al.
Talanta, 186, 413-420 (2018-05-23)
Cytochrome P450s have brought considerable attention to researchers for their significant correlations with metabolic behaviors of procarcinogenic chemicals. To better understand the roles of CYP1A in biological and physiological systems, we developed a novel ratiometric fluorescence probe N-((2-hydroxyl ethoxy) ethyl)- 4-methoxy-1
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