A44509
α-Amino-γ-butyrolactone hydrobromide
99%
Synonym(s):
(±)-α-Amino-γ-butyrolactone hydrobromide, DL-Homoserine lactone hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C4H7NO2 · HBr
CAS Number:
Molecular Weight:
182.02
Beilstein:
4530084
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
99%
form
crystalline
color
white to light yellow
mp
220-225 °C (lit.)
application(s)
peptide synthesis
SMILES string
Br[H].NC1CCOC1=O
InChI
1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
InChI key
MKLNTBLOABOJFZ-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Steven E A Christiaen et al.
Journal of microbiological methods, 87(2), 213-219 (2011-08-23)
A large number of Gram-negative pathogens produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Therefore, strategies to inhibit QS are promising for the control
Sandrine Ghirardi et al.
Microbial ecology, 64(3), 725-737 (2012-05-12)
Rhizosphere competence of fluorescent pseudomonads is a prerequisite for the expression of their beneficial effects on plant growth and health. To date, knowledge on bacterial traits involved in rhizosphere competence is fragmented and derived mostly from studies with model strains.
Amanda L May et al.
Analytical chemistry, 84(3), 1243-1252 (2012-01-13)
A range of acylhomoserine lactones (AHLs) are used as intraspecies quorum sensing signals by Gram-negative bacteria, and the detection and quantitation of these molecules is of interest. This manuscript reports a liquid chromatographic-isotope dilution tandem mass spectrometric method for the
Walter Fast et al.
Trends in biochemical sciences, 37(1), 7-14 (2011-11-22)
N-Acyl-L-homoserine lactones (AHLs) are a major class of quorum-sensing signals used by Gram-negative bacteria to regulate gene expression in a population-dependent manner, thereby enabling group behavior. Enzymes capable of generating and catabolizing AHL signals are of significant interest for the
Mijin Kim et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 66(7), 1424-1430 (2012-08-07)
Biofouling control by quorum sensing (QS) inhibition and the influence of membrane surface characteristics on biofilm formation and QS inhibition were investigated. Pseudomonas putida isolated from the bio-fouled reverse osmosis (RO) membranes in a real plant was used. Acylase was
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